ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D2_1SEM-16.PDB
Scoring matrix: BEM1-D2_1SEM-16_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 19.13
Foldx random average score for Saccharomyces cerevisiae: 18.396

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3206999
Proteins after random average filtering: 7178
 Total fragments: 1353904
Proteins after disorder filtering: 4593
 Total fragments: 79466
Proteins after pattern filtering: 2095
 Total fragments: 8757
Proteins after MINT filtering: 9
 Total fragments: 71


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

19.13

1.45

0.00

Best peptides

FWPRPSLRF

0.00

-1.75

-3.20

         
Interactors      
P38041

VPPQPGSKK

12.46

1.71

0.26

PPQPGSKKG

14.41

-1.93

-3.38

IFESPGRAP

15.09

-1.83

-3.28

P21268

LNLSKPISP

16.54

-1.58

-3.03

P11433

TNSNPSATP

15.67

-1.21

-2.66

P50090

TPTLPPNQH

13.78

-2.86

-4.31

RIVTPTLPP

15.33

-4.88

-6.33

ALPWSPESK

17.39

-0.69

-2.14

P32618

PAPLPSHYS

14.19

-2.29

-3.74

VSYSPSNEP

15.36

-1.08

-2.53

KEPSPKPSH

15.38

-1.30

-2.75

Q03497

KKSFPSKNP

12.27

-2.34

-3.79

KQHKPKVKP

12.98

-5.40

-6.85

IPSRPAPKP

14.35

-5.06

-6.51

P39969

LPPQPGSKK

11.21

1.47

0.02

FKLLPPQPG

14.09

-4.73

-6.18

PPQPGSKKG

14.41

-1.93

-3.38

P22224

TPTFPNANG

15.03

-1.54

-2.99

FPSTPGTID

15.49

-0.79

-2.24

QSPMTPSTP

18.21

-3.37

-4.82

P35735

PLASPHFNP

17.09

-1.41

-2.86

 


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