ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D2_1SEM-14.PDB
Scoring matrix: BEM1-D2_1SEM-14_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 17.5
Foldx random average score for Saccharomyces cerevisiae: 12.307

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3206999
Proteins after random average filtering: 7178
 Total fragments: 1708972
Proteins after disorder filtering: 4293
 Total fragments: 54685
Proteins after pattern filtering: 1880
 Total fragments: 6804
Proteins after MINT filtering: 7
 Total fragments: 47


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

17.50

-2.40

0.00

Best peptides

WMFIILKMI

0.00

-6.13

-3.73

         
Interactors      
P38041

PQSPSFNNR

10.00

-6.03

-3.63

QPPQSPSFN

11.20

-4.31

-1.91

PPSYPSPVQ

12.00

-3.90

-1.50

P21268

SKPISPPPS

11.41

-5.40

-3.00

KPISPPPSL

11.71

-6.35

-3.95

P50090

TPTLPPNQH

11.70

-5.86

-3.46

PTLPPNQHR

11.80

-5.51

-3.11

ALPWSPESK

11.84

-4.04

-1.64

P32618

PSPKPSHKR

8.69

-6.54

-4.14

TPSTSPSGR

9.98

-4.50

-2.10

VPAKEPSPK

10.10

-5.34

-2.94

Q03497

HKPKVKPSK

7.55

-5.01

-2.61

LPPIPPTKS

9.05

-6.64

-4.24

FPSKNPLKN

9.82

-6.65

-4.25

P39969

LSPIPSPTR

8.09

-6.38

-3.98

QPPKSPLLN

10.24

-5.26

-2.86

PEENPITSM

10.35

-6.82

-4.42

P22224

IFPSTPGTI

9.93

-4.80

-2.40

TPTFPNANG

11.94

-5.41

-3.01

 


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