ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D2_1SEM-12.PDB
Scoring matrix: BEM1-D2_1SEM-12_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 12.27
Foldx random average score for Saccharomyces cerevisiae: 10.146

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3214177
Proteins after random average filtering: 7178
 Total fragments: 1332690
Proteins after disorder filtering: 4593
 Total fragments: 77275
Proteins after pattern filtering: 2221
 Total fragments: 12845
Proteins after MINT filtering: 9
 Total fragments: 94


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

12.27

-1.09

0.00

Best peptides

RYFMPRDR

0.00

-4.71

-3.62

         
Interactors      
P38041

PSYPSPVQ

7.97

-3.74

-2.65

FESPGRAP

8.32

-2.23

-1.14

PKPPSYPS

8.50

-3.62

-2.53

P21268

SKPISPPP

8.49

-4.07

-2.98

LSKPISPP

8.72

-2.63

-1.54

NLSKPISP

9.98

-2.62

-1.53

P11433

SNPSATPN

9.71

-2.52

-1.43

P50090

ALPWSPES

7.59

-3.65

-2.56

VTPTLPPN

8.76

-3.61

-2.52

IVTPTLPP

8.97

-3.16

-2.07

P32618

PNLSPRLS

7.26

-5.29

-4.20

SEPAPLPS

7.41

-4.13

-3.04

TNPMHPQS

8.04

-4.84

-3.75

Q03497

PSKNPLKN

6.90

-4.31

-3.22

KFIPSRPA

7.59

-5.72

-4.63

KSFPSKNP

8.03

-3.64

-2.55

P39969

PSYPSPAQ

8.08

-3.96

-2.87

FKLLPPQP

8.18

-5.59

-4.50

PKPPSYPS

8.50

-3.62

-2.53

P22224

GYQSPMTP

8.60

-3.73

-2.64

QSPMTPST

8.89

-3.85

-2.76

PTFPNANG

9.23

-3.06

-1.97

P35735

PHFNPQSS

7.64

-3.23

-2.14

SPHFNPQS

9.42

-4.44

-3.35

LASPHFNP

9.65

-1.70

-0.61

 


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