ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D2_1GCQ-23.PDB
Scoring matrix: BEM1-D2_1GCQ-23_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 13.96
Foldx random average score for Saccharomyces cerevisiae: 11.424

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3221355
Proteins after random average filtering: 7178
 Total fragments: 1523585
Proteins after disorder filtering: 4723
 Total fragments: 75609
Proteins after pattern filtering: 2136
 Total fragments: 11347
Proteins after MINT filtering: 7
 Total fragments: 82


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

13.96

-2.47

0.00

Best peptides

RRLMRRM

0.00

-4.57

-2.10

         
Interactors      
P38041

APKPPSY

7.02

-6.43

-3.96

RAPKPPS

8.53

-4.75

-2.28

KLVPPQP

8.73

-6.26

-3.79

P21268

LSKPISP

7.88

-6.01

-3.54

KPISPPP

8.14

-5.05

-2.58

SKPISPP

10.26

-5.38

-2.91

P50090

TALPWSP

7.74

-6.28

-3.81

PTLPPNQ

9.17

-6.55

-4.08

PWSPESK

11.14

-4.13

-1.66

P32618

GPKVPAK

8.64

-5.19

-2.72

NPVISPY

8.78

-6.16

-3.69

PNLSPRL

8.92

-5.23

-2.76

Q03497

KFIPSRP

4.47

-6.99

-4.52

QPLPPIP

5.57

-7.08

-4.61

RPAPKPP

6.89

-6.80

-4.33

P39969

KLLPPQP

5.98

-7.71

-5.24

RRAPKPP

6.85

-6.89

-4.42

APKPPSY

7.02

-6.43

-3.96

P22224

QSPMTPS

9.89

-4.60

-2.13

YQSPMTP

10.12

-4.68

-2.21

MTPSTPT

11.30

-3.10

-0.63

 


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