ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D2_1GCQ-21.PDB
Scoring matrix: BEM1-D2_1GCQ-21_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAGGAAAA
Foldx wt ligand score: 18.16
Foldx random average score for Saccharomyces cerevisiae: 17.572

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199821
Proteins after random average filtering: 7178
 Total fragments: 1862031
Proteins after disorder filtering: 4451
 Total fragments: 82549
Proteins after pattern filtering: 1696
 Total fragments: 4386
Proteins after MINT filtering: 7
 Total fragments: 34


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAGGAAAA

18.16

-2.17

0.00

Best peptides

EWKLHRPTMK

0.00

-1.77

0.40

         
Interactors      
P38041

QSNPTSPTKQ

12.16

-5.15

-2.98

PTSPTKQTFT

12.99

-5.08

-2.91

PQSPSFNNRY

14.38

-7.48

-5.31

P11433

SNPSATPNME

15.25

-6.84

-4.67

P50090

ALPWSPESKN

16.09

-4.13

-1.96

VTPTLPPNQH

16.68

-6.30

-4.13

P32618

EPSPKPSHKR

12.02

-6.95

-4.78

PIVPGNNTTL

12.66

-4.82

-2.65

NDVPIVPGNN

15.36

-3.53

-1.36

Q03497

THAPTTPNRT

12.69

-6.53

-4.36

TGLPGSPQVS

14.10

-3.08

-0.91

PLPPIPPTKS

15.40

-4.12

-1.95

P39969

PKSPLLNNTR

12.34

-6.33

-4.16

LLPPQPGSKK

15.01

-4.72

-2.55

PPQPGSKKGL

15.58

-5.60

-3.43

P22224

PSTPTFPNAN

14.22

-3.69

-1.52

IFPSTPGTID

16.61

-2.78

-0.61

PTFPNANGVD

17.06

-3.29

-1.12

 


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