ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D2_1GCQ-19.PDB
Scoring matrix: BEM1-D2_1GCQ-19_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 16.22
Foldx random average score for Saccharomyces cerevisiae: 15.757

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3206999
Proteins after random average filtering: 7178
 Total fragments: 1486635
Proteins after disorder filtering: 4474
 Total fragments: 59673
Proteins after pattern filtering: 2028
 Total fragments: 8221
Proteins after MINT filtering: 7
 Total fragments: 66


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

16.22

-1.76

0.00

Best peptides

RKRRMGRCF

0.00

-3.73

-1.97

         
Interactors      
P38041

VPPQPGSKK

10.64

-6.56

-4.80

IFESPGRAP

12.38

-5.85

-4.09

PPQPGSKKG

12.64

-6.19

-4.43

P50090

RIVTPTLPP

11.89

-6.87

-5.11

PTLPPNQHR

12.87

-7.58

-5.82

IVTPTLPPN

14.39

-5.98

-4.22

P32618

VPIVPGNNT

10.87

-4.87

-3.11

GPKVPAKEP

13.23

-6.79

-5.03

PSPKPSHKR

13.94

-5.80

-4.04

Q03497

PPIPPTKSK

10.50

-7.02

-5.26

IPSRPAPKP

11.57

-10.28

-8.52

GKFIPSRPA

12.13

-5.93

-4.17

P39969

LPPQPGSKK

10.41

-7.04

-5.28

PPQPGSKKG

12.64

-6.19

-4.43

PPKSPLLNN

13.13

-7.08

-5.32

P22224

YQSPMTPST

14.02

-3.45

-1.69

PTFPNANGV

14.59

-3.61

-1.85

PMTPSTPTF

14.60

-6.56

-4.80

P35735

PLASPHFNP

15.10

-6.85

-5.09

 


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