ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D2_1GCQ-16.PDB
Scoring matrix: BEM1-D2_1GCQ-16_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 16.76
Foldx random average score for Saccharomyces cerevisiae: 16.126

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3206999
Proteins after random average filtering: 7178
 Total fragments: 1777641
Proteins after disorder filtering: 4703
 Total fragments: 119796
Proteins after pattern filtering: 2267
 Total fragments: 14561
Proteins after MINT filtering: 9
 Total fragments: 110


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

16.76

2.87

0.00

Best peptides

WRPLNSHWA

0.00

-0.49

-3.36

         
Interactors      
P38041

PPQSPSFNN

10.07

1.69

-1.18

FKLVPPQPG

10.99

-3.12

-5.99

CFKLVPPQP

11.05

-2.55

-5.42

P21268

LNLSKPISP

12.88

0.00

-2.87

LSKPISPPP

15.10

-1.06

-3.93

NLSKPISPP

15.73

-1.58

-4.45

P11433

TNSNPSATP

12.59

0.72

-2.15

SNPSATPNM

15.72

1.53

-1.34

P50090

TPTLPPNQH

11.14

-2.22

-5.09

RIVTPTLPP

12.68

-1.51

-4.38

ASTALPWSP

13.84

0.58

-2.29

P32618

PAPLPSHYS

7.65

-2.03

-4.90

PSPKPSHKR

7.71

0.01

-2.86

VSYSPSNEP

10.60

-0.12

-2.99

Q03497

KKSFPSKNP

7.88

-0.45

-3.32

FPSKNPLKN

8.28

-2.67

-5.54

KQHKPKVKP

9.69

-3.40

-6.27

P39969

FKLLPPQPG

9.24

-5.14

-8.01

LSPIPSPTR

9.65

-1.11

-3.98

QPPKSPLLN

10.55

-1.61

-4.48

P22224

FPSTPGTID

10.95

0.22

-2.65

MTPSTPTFP

11.75

0.82

-2.05

TPTFPNANG

12.98

-1.71

-4.58

P35735

PLASPHFNP

9.40

0.52

-2.35

ASPHFNPQS

13.55

0.39

-2.48

SPHFNPQSS

14.48

0.92

-1.95

 


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