ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D2_1GCQ-12.PDB
Scoring matrix: BEM1-D2_1GCQ-12_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 12.66
Foldx random average score for Saccharomyces cerevisiae: 9.401

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3214177
Proteins after random average filtering: 7178
 Total fragments: 1326549
Proteins after disorder filtering: 4541
 Total fragments: 65913
Proteins after pattern filtering: 2090
 Total fragments: 10342
Proteins after MINT filtering: 9
 Total fragments: 78


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

12.66

-1.32

0.00

Best peptides

YWIMPRWR

0.00

-5.24

-3.92

         
Interactors      
P38041

KLVPPQPG

6.84

-5.52

-4.20

PGRAPKPP

7.16

-4.52

-3.20

PKPPSYPS

7.66

-3.15

-1.83

P21268

KPISPPPS

7.72

-5.16

-3.84

SKPISPPP

8.51

-2.73

-1.41

LSKPISPP

9.29

-1.73

-0.41

P11433

SNPSATPN

9.20

-1.92

-0.60

P50090

RIVTPTLP

7.96

-4.56

-3.24

ALPWSPES

8.19

-2.39

-1.07

STALPWSP

8.69

-3.34

-2.02

P32618

PVISPYSS

6.63

-5.36

-4.04

PKVPAKEP

6.71

-5.13

-3.81

PIVPGNNT

7.34

-5.38

-4.06

Q03497

KFIPSRPA

2.83

-8.03

-6.71

KSFPSKNP

5.87

-4.52

-3.20

PSKNPLKN

6.38

-5.10

-3.78

P39969

PRRAPKPP

6.77

-5.00

-3.68

PKPPSYPS

7.66

-3.15

-1.83

SPIPSPTR

7.84

-5.01

-3.69

P22224

GYQSPMTP

7.67

-4.03

-2.71

PTFPNANG

8.83

-2.76

-1.44

PSTPTFPN

9.07

-3.18

-1.86

P35735

PHFNPQSS

6.07

-4.33

-3.01

ASPHFNPQ

8.49

-4.38

-3.06

PLASPHFN

8.59

-1.81

-0.49

 


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