ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-QCF-7.PDB
Scoring matrix: BEM1-D1_JO8-QCF-7_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 13.72
Foldx random average score for Saccharomyces cerevisiae: 11.677

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3214177
Proteins after random average filtering: 7178
 Total fragments: 1536667
Proteins after disorder filtering: 4766
 Total fragments: 100949
Proteins after pattern filtering: 2308
 Total fragments: 16948
Proteins after MINT filtering: 9
 Total fragments: 118


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

13.72

-2.66

0.00

Best peptides

MRKIGTRY

0.00

-2.48

0.18

         
Interactors      
P38041

PPQPGSKK

5.63

-3.88

-1.22

PPSYPSPV

8.02

-5.25

-2.59

VPPQPGSK

8.09

-4.58

-1.92

P21268

KPISPPPS

8.99

-5.37

-2.71

PISPPPSL

9.32

-5.62

-2.96

NLSKPISP

10.29

-4.90

-2.24

P11433

PSATPNME

8.44

-6.62

-3.96

P50090

RIVTPTLP

8.15

-6.24

-3.58

TPTLPPNQ

8.73

-3.89

-1.23

TALPWSPE

9.04

-2.22

0.44

P32618

VPIVPGNN

8.03

-5.77

-3.11

GPKVPAKE

8.14

-5.91

-3.25

VPNLSPRL

8.56

-5.34

-2.68

Q03497

GKFIPSRP

6.51

-8.25

-5.59

PPIPPTKS

6.86

-5.84

-3.18

TGLPGSPQ

7.28

-1.91

0.75

P39969

PPQPGSKK

5.63

-3.88

-1.22

PIPSPTRN

6.92

-5.99

-3.33

SPAQPPKS

7.86

-4.50

-1.84

P22224

PSTPGTID

6.36

-3.25

-0.59

YQSPMTPS

7.89

-3.83

-1.17

TPTFPNAN

9.41

-3.67

-1.01

P35735

ASPHFNPQ

10.11

-3.26

-0.60

PLASPHFN

10.13

-4.61

-1.95

SPHFNPQS

10.23

-3.87

-1.21

 


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