ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-QCF-5.PDB
Scoring matrix: BEM1-D1_JO8-QCF-5_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 18.09
Foldx random average score for Saccharomyces cerevisiae: 18.476

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199821
Proteins after random average filtering: 7178
 Total fragments: 1422691
Proteins after disorder filtering: 4575
 Total fragments: 94540
Proteins after pattern filtering: 2280
 Total fragments: 17908
Proteins after MINT filtering: 9
 Total fragments: 121


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

18.09

3.22

0.00

Best peptides

GKNRPRREPP

0.00

0.95

-2.27

         
Interactors      
P38041

KLVPPQPGSK

11.90

-4.47

-7.69

GRAPKPPSYP

12.48

-3.87

-7.09

PPSYPSPVQP

13.14

-7.72

-10.94

P21268

KPISPPPSLK

12.63

-4.99

-8.21

PLNLSKPISP

13.85

-2.04

-5.26

LNLSKPISPP

14.28

-5.99

-9.21

P11433

SNPSATPNME

17.85

-1.74

-4.96

TNSNPSATPN

17.87

-2.42

-5.64

YTNSNPSATP

18.12

-2.50

-5.72

P50090

GASTALPWSP

12.33

-5.63

-8.85

RIVTPTLPPN

14.02

-4.20

-7.42

TALPWSPESK

17.42

-0.06

-3.28

P32618

GPKVPAKEPS

9.04

-4.15

-7.37

SKSEPAPLPS

13.69

-3.32

-6.54

PKVPAKEPSP

13.72

-2.56

-5.78

Q03497

GKFIPSRPAP

6.37

-3.90

-7.12

IPSRPAPKPP

7.75

-8.62

-11.84

KFIPSRPAPK

10.88

-1.58

-4.80

P39969

GKALSPIPSP

7.81

-7.84

-11.06

VSPRRAPKPP

10.30

-5.80

-9.02

KLLPPQPGSK

11.67

-0.43

-3.65

P22224

GYQSPMTPST

12.35

-2.45

-5.67

SNGYQSPMTP

14.86

-4.87

-8.09

TPSTPTFPNA

16.36

-2.51

-5.73

P35735

PHFNPQSSEK

13.86

-2.39

-5.61

ASPHFNPQSS

17.77

-2.93

-6.15

 


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