ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-QCF-29.PDB
Scoring matrix: BEM1-D1_JO8-QCF-29_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 19.83
Foldx random average score for Saccharomyces cerevisiae: 14.817

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199821
Proteins after random average filtering: 7177
 Total fragments: 1502030
Proteins after disorder filtering: 4239
 Total fragments: 59344
Proteins after pattern filtering: 2111
 Total fragments: 13258
Proteins after MINT filtering: 9
 Total fragments: 99


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

19.83

-2.66

0.00

Best peptides

DHKPRPPRRK

0.00

-9.23

-6.57

         
Interactors      
P38041

CFKLVPPQPG

9.23

-9.06

-6.40

ESPGRAPKPP

10.53

-10.06

-7.40

GRAPKPPSYP

11.85

-7.78

-5.12

P21268

LSKPISPPPS

11.66

-7.64

-4.98

PISPPPSLKK

13.12

-7.64

-4.98

SKPISPPPSL

13.54

-7.24

-4.58

P11433

SNPSATPNME

13.07

-8.52

-5.86

P50090

PTLPPNQHRG

10.13

-11.77

-9.11

VTPTLPPNQH

11.74

-9.40

-6.74

ALPWSPESKN

12.76

-8.13

-5.47

P32618

EPAPLPSHYS

7.95

-9.52

-6.86

EPSPKPSHKR

9.68

-8.35

-5.69

PSPKPSHKRN

10.64

-10.10

-7.44

Q03497

NGKFIPSRPA

6.68

-10.78

-8.12

KPKVKPSKPE

8.69

-9.73

-7.07

SFPSKNPLKN

9.38

-9.88

-7.22

P39969

CFKLLPPQPG

8.17

-9.56

-6.90

SPIPSPTRNS

9.89

-8.17

-5.51

AQPPKSPLLN

10.15

-9.41

-6.75

P22224

MTPSTPTFPN

12.82

-10.29

-7.63

IFPSTPGTID

13.89

-7.80

-5.14

QSPMTPSTPT

14.46

-7.39

-4.73

P35735

ASPHFNPQSS

12.70

-6.82

-4.16

 


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