ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-QCF-25.PDB
Scoring matrix: BEM1-D1_JO8-QCF-25_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 16.75
Foldx random average score for Saccharomyces cerevisiae: 17.240

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3206999
Proteins after random average filtering: 7178
 Total fragments: 1746304
Proteins after disorder filtering: 4657
 Total fragments: 120784
Proteins after pattern filtering: 2285
 Total fragments: 18643
Proteins after MINT filtering: 9
 Total fragments: 135


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

16.75

0.50

0.00

Best peptides

RYRPMGSRM

0.00

-1.58

-2.08

         
Interactors      
P38041

IFESPGRAP

8.71

-4.76

-5.26

VPPQPGSKK

9.42

-4.37

-4.87

ESPGRAPKP

10.95

-5.06

-5.56

P21268

LSKPISPPP

10.88

-4.67

-5.17

SKPISPPPS

15.10

-5.93

-6.43

LNLSKPISP

15.70

-6.42

-6.92

P11433

NSNPSATPN

12.97

-2.78

-3.28

TNSNPSATP

15.29

-1.68

-2.18

P50090

VTPTLPPNQ

14.36

-7.26

-7.76

ALPWSPESK

14.78

-4.86

-5.36

TALPWSPES

15.20

-3.03

-3.53

P32618

ANPVISPYS

11.73

-3.14

-3.64

PSTSPSGRR

12.15

-2.25

-2.75

PSPKPSHKR

12.33

-3.86

-4.36

Q03497

SFPSKNPLK

11.49

-6.58

-7.08

TTGLPGSPQ

11.73

-2.02

-2.52

PLPPIPPTK

12.20

-7.64

-8.14

P39969

SYPSPAQPP

9.26

-6.89

-7.39

LPPQPGSKK

9.29

-3.87

-4.37

AQPPKSPLL

9.42

-5.70

-6.20

P22224

FPSTPGTID

12.71

-1.97

-2.47

SPMTPSTPT

13.44

-2.20

-2.70

GYQSPMTPS

14.85

-3.57

-4.07

P35735

LASPHFNPQ

16.15

-2.20

-2.70

PHFNPQSSE

16.93

-2.01

-2.51

PLASPHFNP

17.05

-3.37

-3.87

 


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