ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-QCF-18.PDB
Scoring matrix: BEM1-D1_JO8-QCF-18_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAAA
Foldx wt ligand score: 14.85
Foldx random average score for Saccharomyces cerevisiae: 12.709

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199821
Proteins after random average filtering: 7178
 Total fragments: 1473331
Proteins after disorder filtering: 4500
 Total fragments: 77014
Proteins after pattern filtering: 2108
 Total fragments: 9644
Proteins after MINT filtering: 9
 Total fragments: 73


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAAA

14.85

0.63

0.00

Best peptides

FPPLNSMWYD

0.00

-0.45

-1.08

         
Interactors      
P38041

RAPKPPSYPS

8.48

-4.65

-5.28

IFESPGRAPK

8.54

-2.94

-3.57

VPPQPGSKKG

8.98

-3.38

-4.01

P21268

LSKPISPPPS

10.79

-2.64

-3.27

P11433

TNSNPSATPN

10.44

-1.50

-2.13

P50090

TPTLPPNQHR

10.40

-4.88

-5.51

RIVTPTLPPN

11.22

-4.08

-4.71

P32618

PSPKPSHKRN

7.53

-3.25

-3.88

PAPLPSHYSS

8.80

-2.76

-3.39

PAKEPSPKPS

9.08

-3.19

-3.82

Q03497

FPSKNPLKNS

6.65

-6.10

-6.73

KQHKPKVKPS

6.80

-3.67

-4.30

KKSFPSKNPL

8.18

-3.22

-3.85

P39969

LSPIPSPTRN

7.40

-2.40

-3.03

LPPQPGSKKG

7.75

-4.51

-5.14

RAPKPPSYPS

8.48

-4.65

-5.28

P22224

FPSTPGTIDS

6.97

-2.87

-3.50

QSPMTPSTPT

11.57

-3.87

-4.50

NGYQSPMTPS

11.59

-1.89

-2.52

P35735

PLASPHFNPQ

9.92

-1.61

-2.24

LASPHFNPQS

12.44

-1.75

-2.38

SPHFNPQSSE

12.65

-1.59

-2.22

 


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