ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-QCF-16.PDB
Scoring matrix: BEM1-D1_JO8-QCF-16_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 14.46
Foldx random average score for Saccharomyces cerevisiae: 13.933

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3206999
Proteins after random average filtering: 7178
 Total fragments: 1574284
Proteins after disorder filtering: 4707
 Total fragments: 113680
Proteins after pattern filtering: 2207
 Total fragments: 11497
Proteins after MINT filtering: 9
 Total fragments: 91


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

14.46

1.31

0.00

Best peptides

RPPLNSIEM

0.00

-0.75

-2.06

         
Interactors      
P38041

RAPKPPSYP

9.46

-3.79

-5.10

IFESPGRAP

9.66

-2.51

-3.82

CFKLVPPQP

9.85

-5.94

-7.25

P21268

LNLSKPISP

11.41

-2.71

-4.02

LSKPISPPP

12.15

-2.90

-4.21

NLSKPISPP

13.24

-1.42

-2.73

P11433

TNSNPSATP

11.49

0.02

-1.29

NPSATPNME

12.39

-1.89

-3.20

SNPSATPNM

13.22

-1.90

-3.21

P50090

TPTLPPNQH

12.79

-3.94

-5.25

LPWSPESKN

12.85

-3.79

-5.10

TALPWSPES

13.33

0.73

-0.58

P32618

VSYSPSNEP

8.17

0.27

-1.04

PSPKPSHKR

8.41

-3.12

-4.43

PAPLPSHYS

8.86

-2.82

-4.13

Q03497

FPSKNPLKN

8.62

-5.81

-7.12

KKSFPSKNP

9.24

-2.39

-3.70

KQHKPKVKP

9.58

-4.03

-5.34

P39969

LSPIPSPTR

6.72

-2.66

-3.97

LPPQPGSKK

8.84

-3.97

-5.28

CFKLLPPQP

9.46

-4.58

-5.89

P22224

FPSTPGTID

8.14

-4.09

-5.40

QSPMTPSTP

11.99

-4.21

-5.52

NGYQSPMTP

12.49

-1.42

-2.73

P35735

PLASPHFNP

11.67

-1.62

-2.93

ASPHFNPQS

11.70

-0.22

-1.53

SPHFNPQSS

13.74

-1.09

-2.40

 


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