ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-QCF-1.PDB
Scoring matrix: BEM1-D1_JO8-QCF-1_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 23.54
Foldx random average score for Saccharomyces cerevisiae: 23.215

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199821
Proteins after random average filtering: 7178
 Total fragments: 1533420
Proteins after disorder filtering: 4581
 Total fragments: 112823
Proteins after pattern filtering: 2311
 Total fragments: 22794
Proteins after MINT filtering: 9
 Total fragments: 159


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

23.54

-1.74

0.00

Best peptides

RRRRPPRDRY

0.00

-1.88

-0.14

         
Interactors      
P38041

SPGRAPKPPS

11.85

-7.36

-5.62

GRAPKPPSYP

14.64

-7.80

-6.06

KPPSYPSPVQ

15.30

-5.87

-4.13

P21268

KPISPPPSLK

14.87

-7.76

-6.02

SKPISPPPSL

15.53

-4.82

-3.08

LNLSKPISPP

16.81

-7.93

-6.19

P11433

NSNPSATPNM

19.29

-4.38

-2.64

YTNSNPSATP

20.19

-6.68

-4.94

TNSNPSATPN

21.00

-4.32

-2.58

P50090

TPTLPPNQHR

15.69

-6.10

-4.36

VTPTLPPNQH

16.73

-4.57

-2.83

ASTALPWSPE

17.20

-5.67

-3.93

P32618

TPSTSPSGRR

12.26

-6.06

-4.32

VPNLSPRLSN

13.57

-9.01

-7.27

VPAKEPSPKP

13.68

-7.94

-6.20

Q03497

IPSRPAPKPP

11.76

-10.55

-8.81

KPKVKPSKPE

14.86

-7.81

-6.07

VKKSFPSKNP

14.97

-7.53

-5.79

P39969

SPRRAPKPPS

11.60

-7.38

-5.64

RRAPKPPSYP

12.57

-12.61

-10.87

VSPRRAPKPP

13.15

-10.36

-8.62

P22224

NGYQSPMTPS

16.93

-7.34

-5.60

TPSTPTFPNA

17.39

-5.82

-4.08

QSPMTPSTPT

18.44

-5.58

-3.84

P35735

SPHFNPQSSE

17.73

-3.98

-2.24

PLASPHFNPQ

20.97

-6.19

-4.45

LASPHFNPQS

22.75

-5.16

-3.42

 


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