ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-LCK-9.PDB
Scoring matrix: BEM1-D1_JO8-LCK-9_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 18.51
Foldx random average score for Saccharomyces cerevisiae: 14.396

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3214177
Proteins after random average filtering: 7178
 Total fragments: 1435369
Proteins after disorder filtering: 4601
 Total fragments: 72338
Proteins after pattern filtering: 2157
 Total fragments: 11489
Proteins after MINT filtering: 8
 Total fragments: 78


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

18.51

-3.49

0.00

Best peptides

FRFGPPRW

0.00

-1.55

1.94

         
Interactors      
P38041

FKLVPPQP

10.19

-8.52

-5.03

RAPKPPSY

11.75

-9.26

-5.77

QPPQSPSF

11.78

-6.15

-2.66

P21268

NLSKPISP

11.34

-7.17

-3.68

KPISPPPS

12.09

-8.17

-4.68

SKPISPPP

12.41

-6.75

-3.26

P50090

RIVTPTLP

12.06

-8.50

-5.01

TPTLPPNQ

12.20

-7.76

-4.27

LPWSPESK

13.08

-6.42

-2.93

P32618

VPNLSPRL

8.88

-7.66

-4.17

VPIVPGNN

12.07

-7.66

-4.17

NPVISPYS

12.28

-6.88

-3.39

Q03497

GKFIPSRP

8.08

-10.18

-6.69

APTTPNRT

10.07

-8.96

-5.47

FPSKNPLK

10.33

-9.96

-6.47

P39969

FKLLPPQP

9.55

-9.21

-5.72

QPPKSPLL

10.02

-7.53

-4.04

RRAPKPPS

11.13

-6.29

-2.80

P22224

FPSTPGTI

11.23

-8.02

-4.53

TPTFPNAN

12.78

-6.13

-2.64

TPSTPTFP

13.37

-7.24

-3.75

P35735

SPHFNPQS

14.08

-5.73

-2.24

 


    Comments or questions on the site? Send a mail to adandatabase@umh.es                                                     
DISCLAIMER