ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-LCK-27.PDB
Scoring matrix: BEM1-D1_JO8-LCK-27_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAAA
Foldx wt ligand score: 11.7
Foldx random average score for Saccharomyces cerevisiae: 13.636

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3206999
Proteins after random average filtering: 7178
 Total fragments: 1595613
Proteins after disorder filtering: 4728
 Total fragments: 137801
Proteins after pattern filtering: 2244
 Total fragments: 15364
Proteins after MINT filtering: 9
 Total fragments: 109


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAAA

11.70

-2.19

0.00

Best peptides

MRWHDEIPK

0.00

-2.37

-0.18

         
Interactors      
P38041

SPGRAPKPP

7.68

-3.58

-1.39

KSQSNPTSP

8.50

-3.69

-1.50

PSYPSPVQP

9.55

-1.49

0.70

P21268

SKPISPPPS

9.14

-5.09

-2.90

LNLSKPISP

10.47

-3.71

-1.52

NLSKPISPP

11.10

-5.02

-2.83

P11433

SNPSATPNM

9.39

-0.96

1.23

NSNPSATPN

9.77

-2.14

0.05

TNSNPSATP

13.42

-3.33

-1.14

P50090

LPWSPESKN

10.72

-6.37

-4.18

IVTPTLPPN

13.32

-4.28

-2.09

P32618

VPAKEPSPK

7.09

-2.84

-0.65

SPSNEPIQP

7.89

-2.79

-0.60

YSPSNEPIQ

8.27

-3.56

-1.37

Q03497

KSFPSKNPL

6.87

-4.46

-2.27

KQTHAPTTP

8.37

-4.97

-2.78

KPSKPEAKS

8.94

-5.58

-3.39

P39969

SPRRAPKPP

7.22

-3.29

-1.10

QPPKSPLLN

7.52

-4.54

-2.35

SPEENPITS

7.89

-1.00

1.19

P22224

MTPSTPTFP

11.36

-4.05

-1.86

NGYQSPMTP

11.71

-3.10

-0.91

PSTPGTIDS

12.05

-2.50

-0.31

P35735

LASPHFNPQ

7.96

-4.53

-2.34

ASPHFNPQS

11.10

-5.77

-3.58

PLASPHFNP

13.36

-2.91

-0.72

 


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