ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-LCK-25.PDB
Scoring matrix: BEM1-D1_JO8-LCK-25_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 20.14
Foldx random average score for Saccharomyces cerevisiae: 15.046

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3206999
Proteins after random average filtering: 7178
 Total fragments: 1443448
Proteins after disorder filtering: 4522
 Total fragments: 87673
Proteins after pattern filtering: 2215
 Total fragments: 15580
Proteins after MINT filtering: 8
 Total fragments: 107


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

20.14

-0.36

0.00

Best peptides

RFPPGREPR

0.00

-0.12

0.24

         
Interactors      
P38041

FESPGRAPK

8.70

-1.97

-1.61

IFESPGRAP

11.64

-4.80

-4.44

PKPPSYPSP

11.66

-5.37

-5.01

P21268

SKPISPPPS

12.19

-4.66

-4.30

LNLSKPISP

12.62

-5.72

-5.36

KPISPPPSL

14.29

-4.45

-4.09

P50090

PTLPPNQHR

11.14

-4.50

-4.14

IVTPTLPPN

12.49

-4.02

-3.66

VTPTLPPNQ

12.54

-7.43

-7.07

P32618

DVPIVPGNN

9.42

-5.25

-4.89

PNLSPRLSN

9.69

-1.70

-1.34

SYSPSNEPI

11.05

-3.65

-3.29

Q03497

SFPSKNPLK

8.11

-5.19

-4.83

KFIPSRPAP

8.23

-2.96

-2.60

HKPKVKPSK

9.66

-6.13

-5.77

P39969

LLPPQPGSK

10.82

-5.09

-4.73

QPPKSPLLN

10.98

-4.37

-4.01

AQPPKSPLL

11.38

-5.53

-5.17

P22224

STPTFPNAN

10.93

-2.68

-2.32

IFPSTPGTI

11.90

-5.70

-5.34

GYQSPMTPS

12.56

-4.67

-4.31

P35735

PHFNPQSSE

13.18

-1.73

-1.37

PLASPHFNP

13.23

-4.75

-4.39

ASPHFNPQS

14.05

-1.30

-0.94

 


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