ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-LCK-23.PDB
Scoring matrix: BEM1-D1_JO8-LCK-23_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 12.45
Foldx random average score for Saccharomyces cerevisiae: 11.853

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3221355
Proteins after random average filtering: 7178
 Total fragments: 1601306
Proteins after disorder filtering: 4883
 Total fragments: 104004
Proteins after pattern filtering: 2132
 Total fragments: 9008
Proteins after MINT filtering: 9
 Total fragments: 68


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

12.45

0.07

0.00

Best peptides

RPWKPRM

0.00

1.46

1.40

         
Interactors      
P38041

RAPKPPS

7.31

-3.07

-3.13

SPGRAPK

8.56

-1.87

-1.94

SPVQPPQ

9.35

-1.44

-1.50

P21268

KPISPPP

9.42

-3.10

-3.17

P11433

SNPSATP

11.28

-1.30

-1.37

NPSATPN

11.34

-0.70

-0.76

P50090

LPWSPES

9.82

-3.33

-3.40

TPTLPPN

10.30

-1.23

-1.29

TALPWSP

11.43

-2.87

-2.94

P32618

PNLSPRL

5.93

-2.92

-2.98

TNPMHPQ

8.69

-2.00

-2.06

SEPAPLP

8.75

-2.04

-2.11

Q03497

FPSKNPL

8.65

-2.05

-2.11

KPSKPEA

8.67

-0.77

-0.83

HKPKVKP

8.87

-2.07

-2.13

P39969

RAPKPPS

7.31

-3.07

-3.13

QPPKSPL

7.50

-2.51

-2.57

SPRRAPK

7.76

-2.51

-2.57

P22224

TPSTPTF

10.34

-0.75

-0.81

QSPMTPS

10.47

-1.47

-1.53

MTPSTPT

10.88

-1.08

-1.15

P35735

ASPHFNP

9.72

-0.25

-0.32

PLASPHF

11.01

-0.51

-0.57

 


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