ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-LCK-20.PDB
Scoring matrix: BEM1-D1_JO8-LCK-20_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 20.3
Foldx random average score for Saccharomyces cerevisiae: 21.079

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3206999
Proteins after random average filtering: 7178
 Total fragments: 1448686
Proteins after disorder filtering: 4596
 Total fragments: 92805
Proteins after pattern filtering: 2094
 Total fragments: 8947
Proteins after MINT filtering: 7
 Total fragments: 68


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

20.30

-3.46

0.00

Best peptides

RRPFRGRSR

0.00

-0.69

2.77

         
Interactors      
P38041

VQPPQSPSF

15.33

-6.35

-2.89

VPPQPGSKK

16.51

-6.14

-2.68

IFESPGRAP

16.89

-5.74

-2.28

P50090

PTLPPNQHR

18.72

-7.15

-3.69

RIVTPTLPP

19.72

-5.92

-2.46

LPWSPESKN

20.36

-5.51

-2.05

P32618

PSPKPSHKR

16.45

-7.96

-4.50

KEPSPKPSH

16.85

-6.61

-3.15

KVPAKEPSP

17.14

-6.64

-3.18

Q03497

HKPKVKPSK

14.69

-5.76

-2.30

PKPPSSASA

16.94

-4.70

-1.24

APTTPNRTS

17.46

-4.95

-1.49

P39969

RRAPKPPSY

14.12

-6.39

-2.93

LPPQPGSKK

15.70

-6.51

-3.05

PEENPITSM

17.52

-7.69

-4.23

P22224

SPMTPSTPT

19.91

-3.38

0.08

YQSPMTPST

20.15

-4.73

-1.27

TPTFPNANG

20.22

-4.60

-1.14

P35735

PHFNPQSSE

19.89

-4.81

-1.35

 


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