ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-LCK-14.PDB
Scoring matrix: BEM1-D1_JO8-LCK-14_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 14.84
Foldx random average score for Saccharomyces cerevisiae: 12.140

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3206999
Proteins after random average filtering: 7178
 Total fragments: 1764088
Proteins after disorder filtering: 4601
 Total fragments: 73672
Proteins after pattern filtering: 2045
 Total fragments: 8306
Proteins after MINT filtering: 7
 Total fragments: 51


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

14.84

-3.76

0.00

Best peptides

RPFGKFKKL

0.00

-0.33

3.43

         
Interactors      
P38041

KPPSYPSPV

9.32

-5.48

-1.72

VPPQPGSKK

9.97

-5.17

-1.41

PSPVQPPQS

10.56

-4.60

-0.84

P21268

KPISPPPSL

8.89

-6.58

-2.82

SKPISPPPS

12.04

-4.55

-0.79

P50090

TPTLPPNQH

9.61

-5.91

-2.15

ALPWSPESK

11.93

-4.02

-0.26

LPWSPESKN

11.99

-3.22

0.54

P32618

VPNLSPRLS

8.81

-6.40

-2.64

NPVISPYSS

9.43

-5.16

-1.40

DVPIVPGNN

9.64

-4.87

-1.11

Q03497

LPPIPPTKS

7.83

-7.28

-3.52

KPSKPEAKS

8.84

-3.67

0.09

FPSKNPLKN

9.24

-6.12

-2.36

P39969

PEENPITSM

9.64

-5.32

-1.56

QPPKSPLLN

9.65

-4.84

-1.08

LPPQPGSKK

9.90

-5.05

-1.29

P22224

PSTPTFPNA

11.18

-4.05

-0.29

FPSTPGTID

11.73

-3.60

0.16

 


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