ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-LCK-13.PDB
Scoring matrix: BEM1-D1_JO8-LCK-13_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 12.04
Foldx random average score for Saccharomyces cerevisiae: 16.890

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3214177
Proteins after random average filtering: 7178
 Total fragments: 1603824
Proteins after disorder filtering: 4794
 Total fragments: 130579
Proteins after pattern filtering: 2333
 Total fragments: 19316
Proteins after MINT filtering: 9
 Total fragments: 125


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

12.04

-1.05

0.00

Best peptides

RPRPHPLW

0.00

-0.20

0.85

         
Interactors      
P38041

KPPSYPSP

5.58

-6.04

-4.99

APKPPSYP

7.03

-5.02

-3.97

KLVPPQPG

7.51

-4.80

-3.75

P21268

KPISPPPS

6.63

-5.08

-4.03

PISPPPSL

9.34

-4.84

-3.79

LSKPISPP

11.18

-1.99

-0.94

P11433

SNPSATPN

10.38

-1.53

-0.48

NSNPSATP

13.52

-0.78

0.27

P50090

LPWSPESK

7.71

-5.58

-4.53

IVTPTLPP

10.18

-1.58

-0.53

TALPWSPE

11.42

-1.69

-0.64

P32618

KEPSPKPS

7.36

-3.77

-2.72

EPSPKPSH

7.98

-5.38

-4.33

KSEPAPLP

8.07

-2.92

-1.87

Q03497

RPAPKPPS

5.50

-6.87

-5.82

FIPSRPAP

6.71

-4.97

-3.92

LPGSPQVS

7.17

-5.90

-4.85

P39969

KPPSYPSP

5.58

-6.04

-4.99

RRAPKPPS

5.59

-3.99

-2.94

APKPPSYP

7.03

-5.02

-3.97

P22224

YQSPMTPS

9.49

-3.00

-1.95

GYQSPMTP

10.53

-3.97

-2.92

IFPSTPGT

10.61

-2.74

-1.69

P35735

PLASPHFN

8.61

-7.75

-6.70

LASPHFNP

15.26

-4.18

-3.13

 


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