ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-LCK-12.PDB
Scoring matrix: BEM1-D1_JO8-LCK-12_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 8.91
Foldx random average score for Saccharomyces cerevisiae: 11.069

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3214177
Proteins after random average filtering: 7178
 Total fragments: 1799283
Proteins after disorder filtering: 4809
 Total fragments: 120172
Proteins after pattern filtering: 2267
 Total fragments: 15989
Proteins after MINT filtering: 9
 Total fragments: 113


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

8.91

-1.18

0.00

Best peptides

RDAKRRFR

0.00

1.02

2.20

         
Interactors      
P38041

GRAPKPPS

6.40

-2.62

-1.44

FESPGRAP

7.04

-2.50

-1.32

PQSPSFNN

8.06

-0.21

0.97

P21268

NLSKPISP

6.10

-3.25

-2.07

PISPPPSL

7.58

-1.75

-0.57

SKPISPPP

8.49

-2.01

-0.83

P11433

NPSATPNM

9.28

-0.74

0.44

PSATPNME

10.25

-2.85

-1.67

P50090

STALPWSP

6.54

-2.20

-1.02

ALPWSPES

9.20

-2.14

-0.96

IVTPTLPP

9.49

-4.14

-2.96

P32618

VPAKEPSP

7.35

-1.70

-0.52

SEPAPLPS

7.53

-3.57

-2.39

NDVPIVPG

7.92

-4.13

-2.95

Q03497

KFIPSRPA

6.83

-5.45

-4.27

RPAPKPPS

7.25

-2.54

-1.36

PKVKPSKP

7.26

-3.01

-1.83

P39969

PKSPLLNN

5.08

-2.64

-1.46

RRAPKPPS

6.36

-3.59

-2.41

SPAQPPKS

7.26

-1.88

-0.70

P22224

TPSTPTFP

7.99

-2.65

-1.47

YQSPMTPS

9.46

-1.60

-0.42

PTFPNANG

9.83

-2.43

-1.25

P35735

PLASPHFN

7.65

-2.38

-1.20

LASPHFNP

7.85

-4.01

-2.83

 


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