ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-LCK-11.PDB
Scoring matrix: BEM1-D1_JO8-LCK-11_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 15.16
Foldx random average score for Saccharomyces cerevisiae: 12.559

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3221355
Proteins after random average filtering: 7178
 Total fragments: 1302475
Proteins after disorder filtering: 4543
 Total fragments: 73501
Proteins after pattern filtering: 2207
 Total fragments: 12091
Proteins after MINT filtering: 9
 Total fragments: 87


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

15.16

-1.48

0.00

Best peptides

FRWWPRR

0.00

0.74

2.22

         
Interactors      
P38041

PPSYPSP

9.64

-6.67

-5.19

GRAPKPP

10.15

-3.59

-2.11

RAPKPPS

10.31

-5.24

-3.76

P21268

KPISPPP

10.19

-5.91

-4.43

SKPISPP

11.85

-3.21

-1.73

PISPPPS

11.95

-4.63

-3.15

P11433

PSATPNM

12.33

-4.27

-2.79

P50090

TPTLPPN

8.78

-5.52

-4.04

ALPWSPE

10.66

-2.74

-1.26

PWSPESK

12.45

-2.14

-0.66

P32618

PAPLPSH

8.35

-5.32

-3.84

PSPKPSH

8.40

-3.78

-2.30

VPNLSPR

8.48

-3.17

-1.69

Q03497

FPSKNPL

8.07

-5.38

-3.90

SRPAPKP

8.63

-5.17

-3.69

APTTPNR

8.73

-5.78

-4.30

P39969

PRRAPKP

8.79

-5.51

-4.03

RRAPKPP

8.83

-3.61

-2.13

PIPSPTR

9.32

-4.93

-3.45

P22224

FPSTPGT

9.95

-6.56

-5.08

TPTFPNA

10.30

-4.69

-3.21

TPSTPTF

11.01

-3.61

-2.13

P35735

SPHFNPQ

10.21

-3.58

-2.10

PHFNPQS

12.06

-3.79

-2.31

ASPHFNP

12.24

-3.31

-1.83

 


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