ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BBC1_1ZUK3-19.PDB
Scoring matrix: BBC1_1ZUK3-19_mat
Uniprot code: P47068
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 18.13
Foldx random average score for Saccharomyces cerevisiae: 18.229

Available information for P47068 in MINT (Nov 2008):
Nš of interacting proteins: 45
 Proteins belonging to other specie: 0
Nš of interactions described: 64
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2175611
Proteins after random average filtering: 5078
 Total fragments: 973099
Proteins after disorder filtering: 3036
 Total fragments: 43197
Proteins after pattern filtering: 1406
 Total fragments: 6427
Proteins after MINT filtering: 27
 Total fragments: 290

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

18.13

3.27

0.00

Best peptides

IPKRRGRYG

0.00

-1.12

-4.39

         
Interactors      
Q06604

GPRMPSRGR

10.69

-4.40

-7.67

PPLPTRRDH

11.19

-3.35

-6.62

EKGPRMPSR

12.31

-2.85

-6.12

P24583

PPQPRKHDK

11.33

-3.89

-7.16

APLPPQPRK

12.60

-4.39

-7.66

LPPQPRKHD

15.49

-2.36

-5.63

Q06625

IPLPKDAPK

12.92

-4.07

-7.34

LPPIPLPKD

16.23

-0.46

-3.73

SVGIPGTPR

16.75

-3.36

-6.63

P19812

PIFRPGNIF

12.05

-4.70

-7.97

DHSPIFRPG

12.08

-3.82

-7.09

EPRPRRIPP

14.39

-6.09

-9.36

P53182

SRRNPGKPP

17.29

-4.96

-8.23

P53169

PIMPTLPPR

16.00

-6.64

-9.91

SPAQPSASL

16.47

-2.33

-5.60

VPIMPTLPP

16.67

-3.99

-7.26

Q12043

KTAAPGRFP

13.54

-5.49

-8.76

PSTSPQRSK

14.37

-1.54

-4.81

FPSTPLFEK

15.18

-1.91

-5.18

P40453

PDLPIRLRK

13.03

-4.85

-8.12

VPEPPSWKP

13.76

-5.93

-9.20

PPDLPIRLR

14.45

-5.41

-8.68

P53971

RKCHPGKCP

15.70

-5.84

-9.11

PFLPSSLKT

16.24

-2.39

-5.66

NPLDPNSCG

16.37

-0.52

-3.79

Q12168

PPPVPNRPG

11.26

-5.04

-8.31

VPNRPGGTT

13.63

-0.40

-3.67

PPVPNRPGG

13.82

-4.66

-7.93

P27472

PLSVPGSPR

13.76

-3.77

-7.04

PGSPRDLRS

13.96

-1.67

-4.94

VPGSPRDLR

15.92

-4.50

-7.77

P36006

PPPPMGQPK

12.33

-6.02

-9.29

PKNPGGLSG

12.85

-3.36

-6.63

MGQPKDPKF

13.94

-3.89

-7.16

P32790

APAPLDPFK

13.18

-3.46

-6.73

PPAMPARPT

13.33

-3.15

-6.42

PLDPFKTGG

14.29

-4.25

-7.52

Q06412

PKSPRDSSK

12.29

-2.23

-5.50

PPPPPLLYS

14.24

-3.86

-7.13

PPPPLSTSR

14.82

-4.98

-8.25

P34226

PVPPPQLHL

15.03

-7.37

-10.64

P36102

LKYPRIYPP

15.62

-5.65

-8.92

KYPRIYPPP

16.84

-6.14

-9.41

NYDPFNAPI

16.87

-3.46

-6.73

P53933

PPPLPNRQL

14.49

-7.65

-10.92

PPPIPSTQK

15.12

-3.40

-6.67

VAPPPLPNR

15.31

-4.99

-8.26

Q04439

APPPPGMQN

12.64

-3.48

-6.75

PPPPGMQNK

14.44

-4.53

-7.80

PPPPSSKPK

14.71

-5.09

-8.36

Q12446

PPPPPHRHV

10.15

-6.08

-9.35

PPPRRGPAP

11.75

-4.66

-7.93

PPPPPMRTT

13.00

-4.26

-7.53

P39969

LPPQPGSKK

11.19

-3.89

-7.16

PPQPGSKKG

11.26

-3.32

-6.59

VSPRRAPKP

14.24

-3.36

-6.63

P37370

APPIPGMGA

12.78

-0.89

-4.16

PKVPQNRPH

13.06

-4.22

-7.49

PKPRPFQNK

13.14

-5.77

-9.04

P53739

FPQEPSPKI

13.70

-2.84

-6.11

RRSPSTPIM

16.21

-3.90

-7.17

TPIMPSQNS

16.83

-1.58

-4.85

P40563

PSERPKRRA

10.42

-2.61

-5.88

PPTPAGTPN

15.49

-2.37

-5.64

PPPVPKKPS

16.09

-3.85

-7.12

P40325

RPPRPAANL

12.86

-4.90

-8.17

LYVQPGDPR

14.56

-3.36

-6.63

QPGDPRLGG

15.14

-2.13

-5.40

Q04195

GNEPIQFPF

16.01

-4.28

-7.55

PQNVPIRTN

16.38

-1.44

-4.71

APPPTNPDA

17.03

-0.86

-4.13

Q07555

LPLPASRPS

12.45

-2.67

-5.94

PASRPSLNL

13.48

-3.33

-6.60

KTKVPKLPL

15.53

-5.68

-8.95

Q05080

LRQKPDKPR

14.13

-4.14

-7.41

KPDKPRPIV

14.61

-4.94

-8.21

RQKPDKPRP

17.43

-5.74

-9.01

 


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