ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BBC1_1ZUK2-27.PDB
Scoring matrix: BBC1_1ZUK2-27_mat
Uniprot code: P47068
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAAA
Foldx wt ligand score: 14.82
Foldx random average score for Saccharomyces cerevisiae: 17.052

Available information for P47068 in MINT (Nov 2008):
Nš of interacting proteins: 45
 Proteins belonging to other specie: 0
Nš of interactions described: 64
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2175611
Proteins after random average filtering: 5078
 Total fragments: 1474604
Proteins after disorder filtering: 3279
 Total fragments: 116823
Proteins after pattern filtering: 1619
 Total fragments: 15972
Proteins after MINT filtering: 28
 Total fragments: 792


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAAA

14.82

-6.21

0.00

Best peptides

RRKRPPIWR

0.00

-7.81

-1.60

         
Interactors      
Q06604

KGPRMPSRG

8.10

-6.46

-0.25

FEKGPRMPS

9.46

-9.06

-2.85

LPTRPNKAE

10.73

-6.83

-0.62

P24583

RANAPLPPQ

8.07

-9.28

-3.07

NAPLPPQPR

11.35

-7.49

-1.28

APLPPQPRK

12.77

-7.51

-1.30

Q06625

VLTLPPIPL

11.53

-6.69

-0.48

TLPPIPLPK

12.64

-6.72

-0.51

IPLPKDAPK

12.89

-7.08

-0.87

P19812

RPRRIPPTD

5.96

-9.17

-2.96

PRPRRIPPT

9.28

-8.32

-2.11

PIFRPGNIF

10.21

-7.06

-0.85

P53182

SRRNPGKPP

9.18

-10.06

-3.85

SSRRNPGKP

9.58

-6.55

-0.34

P53169

MPTLPPRPY

11.31

-8.17

-1.96

TANSVPIMP

11.70

-6.74

-0.53

YSPAQPSAS

12.47

-7.00

-0.79

Q12043

TLFNPSRFP

10.23

-7.39

-1.18

NPSRFPMDA

10.43

-6.07

0.14

FNPSRFPMD

10.72

-8.46

-2.25

P40453

LRKRPPPPP

5.50

-9.87

-3.66

RKRPPPPPP

7.49

-11.12

-4.91

RLRKRPPPP

9.77

-10.38

-4.17

P53971

RKCHPGKCP

7.87

-9.77

-3.56

PGKCPPCLE

11.24

-6.90

-0.69

CHPGKCPPC

11.88

-6.13

0.08

Q12168

RGPPPLPPR

8.55

-8.99

-2.78

TNRGPPPLP

10.01

-7.08

-0.87

KVQHPVPKP

10.43

-9.53

-3.32

P27472

RPLSVPGSP

12.65

-5.52

0.69

VPGSPRDLR

13.50

-7.88

-1.67

SVPGSPRDL

14.73

-4.59

1.62

P36006

SNKKPKNPG

10.83

-7.73

-1.52

KPKNPGGLS

11.18

-7.07

-0.86

IPIPPPPPP

11.68

-8.62

-2.41

P32790

KPPRPTSTT

10.34

-6.43

-0.22

SAPAPLDPF

11.31

-7.75

-1.54

PPPAMPARP

12.68

-7.61

-1.40

Q06440

RTPKVEPSK

13.23

-4.86

1.35

DRTPKVEPS

14.91

-6.81

-0.60

Q06412

KERRPPPPP

6.77

-8.98

-2.77

RRPPPPPPL

7.92

-10.28

-4.07

VKERRPPPP

8.15

-8.99

-2.78

P34226

TPTNSPSPG

12.64

-4.73

1.48

VPVPPPQLH

13.19

-7.62

-1.41

EEDFVPVPP

15.22

-3.98

2.23

P36102

NLKYPRIYP

7.65

-9.47

-3.26

KYPRIYPPP

8.00

-7.95

-1.74

YDPFNAPIF

11.22

-5.42

0.79

P53933

TRRRPPPPP

4.74

-9.35

-3.14

RTRRRPPPP

5.24

-10.69

-4.48

RRRPPPPPI

7.23

-10.84

-4.63

Q04439

SNARPSPPT

7.33

-6.81

-0.60

KKPAPPPPG

8.77

-9.66

-3.45

RQANIPPPP

8.85

-8.72

-2.51

Q12446

RNNRPVPPP

5.36

-10.01

-3.80

RGPAPPPPP

6.68

-10.56

-4.35

RLPAPPPPP

7.39

-10.09

-3.88

P39969

SPRRAPKPP

7.92

-7.69

-1.48

VSPRRAPKP

9.44

-6.10

0.11

PRRAPKPPS

9.94

-8.25

-2.04

P37370

RPHMPSVRP

8.69

-8.52

-2.31

SSAAPPIPI

8.81

-8.37

-2.16

SSSAPPIPD

8.88

-8.30

-2.09

P53739

RRRSPSTPI

8.58

-8.77

-2.56

RSPSTPIMP

9.26

-7.16

-0.95

NSFFPQEPS

9.73

-6.20

0.01

P40563

RRAPPPVPK

8.73

-9.08

-2.87

KRRAPPPVP

9.44

-10.02

-3.81

PSERPKRRA

9.94

-6.66

-0.45

P40325

RPPRPAANL

7.07

-7.36

-1.15

SQPRPPPRP

7.47

-7.89

-1.68

HQSRPHQRP

7.59

-8.46

-2.25

Q04195

SSSHPSEPI

9.43

-9.21

-3.00

RAPPPTNPD

10.48

-9.14

-2.93

RGNEPIQFP

10.99

-4.65

1.56

Q07555

TKVPKLPLP

11.98

-6.54

-0.33

VPKLPLPAS

12.31

-6.63

-0.42

WKTKVPKLP

12.69

-6.78

-0.57

Q05080

RQKPDKPRP

9.85

-8.76

-2.55

LRQKPDKPR

12.30

-5.98

0.23

QKPDKPRPI

12.41

-5.23

0.98

 


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