ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BBC1_1ZUK2-23.PDB
Scoring matrix: BBC1_1ZUK2-23_mat
Uniprot code: P47068
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 10.52
Foldx random average score for Saccharomyces cerevisiae: 9.953

Available information for P47068 in MINT (Nov 2008):
Nš of interacting proteins: 45
 Proteins belonging to other specie: 0
Nš of interactions described: 64
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2185767
Proteins after random average filtering: 5078
 Total fragments: 1131475
Proteins after disorder filtering: 3406
 Total fragments: 84081
Proteins after pattern filtering: 1590
 Total fragments: 10128
Proteins after MINT filtering: 28
 Total fragments: 620


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

10.52

-2.31

0.00

Best peptides

RPLMPMF

0.00

-5.62

-3.31

         
Interactors      
Q06604

RVKPAPP

4.79

-5.46

-3.15

KPKPTPP

6.01

-4.53

-2.22

PPLPTRR

6.64

-2.43

-0.12

P24583

LPPQPRK

6.52

-4.02

-1.70

APLPPQP

7.04

-3.26

-0.94

PPQPRKH

7.42

-1.42

0.90

Q06625

LTLPPIP

6.12

-4.02

-1.70

TLPPIPL

7.19

-0.89

1.42

PPIPLPK

8.88

-2.29

0.02

P19812

RPRRIPP

3.41

-7.33

-5.02

PRPRRIP

8.12

-3.68

-1.37

SPEASPS

8.49

-1.90

0.42

P53182

RNPGKPP

5.18

-5.66

-3.35

RRNPGKP

5.83

-6.18

-3.86

P53169

TLPPRPY

6.34

-2.58

-0.27

YSPAQPS

6.69

-3.13

-0.81

PTLPPRP

6.83

-4.67

-2.36

Q12043

FPLQPLP

4.36

-4.69

-2.38

QPLPSPS

6.55

-3.40

-1.09

FNPSRFP

6.63

-4.01

-1.69

P40453

RKRPPPP

3.40

-5.24

-2.93

RPPPPPP

4.20

-5.77

-3.45

KRPPPPP

6.31

-3.31

-1.00

P53971

KACPFLP

7.48

-3.02

-0.71

PFLPSSL

7.65

-2.97

-0.66

NPDPNPL

7.65

-0.04

2.27

Q12168

RGPPPLP

4.70

-4.80

-2.48

PPLPPRA

5.81

-2.08

0.23

HPVPKPN

7.41

-2.79

-0.48

P27472

RPLSVPG

4.46

-5.59

-3.27

LSVPGSP

8.87

-3.45

-1.14

VPGSPRD

9.04

-1.76

0.55

P36006

KPKNPGG

6.80

-2.65

-0.33

KKPKNPG

7.07

-3.37

-1.06

PPPPPMG

7.14

-3.35

-1.04

P32790

KPPRPTS

6.47

-3.72

-1.41

MPARPTA

7.29

-3.78

-1.46

PIKPPRP

7.38

-2.68

-0.37

Q06440

RTPKVEP

5.83

-5.48

-3.17

Q06412

RPPPPPP

4.20

-5.77

-3.45

RRPPPPP

4.42

-4.81

-2.49

FTKPPPP

5.43

-4.45

-2.14

P34226

PVPPPQL

8.37

-2.66

-0.35

TPTNSPS

8.53

-0.57

1.75

VPVPPPQ

8.73

-1.03

1.28

P36102

KYPRIYP

6.65

-4.96

-2.65

YPRIYPP

7.68

-1.95

0.36

PPMQPPP

8.23

-3.71

-1.40

P53933

RRRPPPP

3.30

-5.38

-3.06

RPPPPPI

3.86

-5.91

-3.60

RRPPPPP

4.42

-4.81

-2.49

Q04439

KPKEPMF

3.91

-4.20

-1.89

RPSPPTA

5.34

-3.37

-1.06

KKPAPPP

6.77

-5.28

-2.97

Q12446

RPLPQLP

3.46

-6.83

-4.52

RPVPPPP

4.67

-5.61

-3.30

RLPAPPP

5.03

-6.32

-4.01

P39969

RAPKPPS

4.54

-4.84

-2.52

KLLPPQP

5.47

-6.05

-3.73

RRAPKPP

5.50

-4.48

-2.17

P37370

MPKPRPF

4.39

-4.09

-1.77

RPHMPSV

4.51

-5.10

-2.78

RPSPISP

5.62

-5.15

-2.84

P53739

RSPSTPI

6.07

-5.33

-3.02

FPQEPSP

6.25

-1.96

0.35

RRSPSTP

6.31

-6.10

-3.78

P40563

RAPPPVP

5.47

-5.68

-3.36

QPQGPSD

7.05

-2.52

-0.21

TPAGTPN

7.53

-1.52

0.79

P40325

RPPRPAA

4.25

-5.31

-2.99

RPPPRPQ

4.59

-5.46

-3.15

RPHQRPS

4.76

-4.09

-1.77

Q04195

EPIQFPF

7.80

-2.97

-0.66

LPQNVPI

7.83

-2.20

0.11

HPSEPII

7.99

-2.30

0.02

Q07555

KVPKLPL

6.52

-4.05

-1.73

PKLPLPA

7.48

-3.00

-0.69

TKVPKLP

7.94

-2.68

-0.37

Q05080

RQKPDKP

4.34

-5.68

-3.36

KPDKPRP

5.04

-2.70

-0.39

PDKPRPI

8.08

-2.22

0.09

 


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