ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BBC1_1ZUK2-10.PDB
Scoring matrix: BBC1_1ZUK2-10_mat
Uniprot code: P47068
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 13.54
Foldx random average score for Saccharomyces cerevisiae: 18.526

Available information for P47068 in MINT (Nov 2008):
Nš of interacting proteins: 45
 Proteins belonging to other specie: 0
Nš of interactions described: 64
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2180689
Proteins after random average filtering: 5078
 Total fragments: 1169169
Proteins after disorder filtering: 3367
 Total fragments: 121252
Proteins after pattern filtering: 1633
 Total fragments: 13495
Proteins after MINT filtering: 28
 Total fragments: 712


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

13.54

1.48

0.00

Best peptides

RPRIGRRR

0.00

-8.83

-10.31

         
Interactors      
Q06604

PSPPAKRI

9.32

-4.91

-6.39

RVKPAPPV

9.46

-4.43

-5.91

KPLLPTRP

10.18

-4.98

-6.46

P24583

LPPQPRKH

11.68

-5.08

-6.56

NAPLPPQP

14.63

-1.52

-3.00

PPQPRKHD

15.14

-0.31

-1.79

Q06625

GPKQGPVT

8.69

-3.23

-4.71

VGIPGTPR

10.28

-2.10

-3.58

LPPIPLPK

13.60

-3.12

-4.60

P19812

EPRPRRIP

12.11

-1.34

-2.82

PIFRPGNI

12.62

-2.73

-4.21

KTSPSNSP

13.41

-1.34

-2.82

P53182

RRNPGKPP

7.67

-4.16

-5.64

SRRNPGKP

12.77

-2.28

-3.76

P53169

MPTLPPRP

9.62

-6.46

-7.94

VPIMPTLP

12.04

-3.45

-4.93

ANSVPIMP

13.61

-1.99

-3.47

Q12043

TAAPGRFP

6.92

-2.90

-4.38

LFNPSRFP

11.22

-2.34

-3.82

QPLPSPSS

11.95

-2.03

-3.51

P40453

CPRCGPTA

7.31

-3.79

-5.27

VPEPPSWK

10.44

-3.13

-4.61

PPDLPIRL

11.08

-4.79

-6.27

P53971

KCHPGKCP

7.07

-4.08

-5.56

PFLPSSLK

12.02

-2.02

-3.50

NPDPNPLD

12.06

1.51

0.03

Q12168

PNRPGGTT

7.46

-3.09

-4.57

PPPLPPRA

11.79

-4.27

-5.75

DPYFPQFR

12.61

-2.44

-3.92

P27472

LSVPGSPR

8.65

-3.22

-4.70

SVPGSPRD

13.88

-2.36

-3.84

VPGSPRDL

14.14

-0.96

-2.44

P36006

PKNPGGLS

7.61

-2.40

-3.88

PPPMGQPK

9.34

-4.88

-6.36

PPPPPPMG

12.02

-3.92

-5.40

P32790

TVPAAPVS

11.07

-2.24

-3.72

GPPPAMPA

11.38

-2.45

-3.93

PPAMPARP

11.59

-4.88

-6.36

Q06440

TPKVEPSK

17.82

1.86

0.38

Q06412

FSPNSPKS

12.14

-2.01

-3.49

PPPPPLLY

12.16

-3.21

-4.69

KPPPPLST

12.22

-2.62

-4.10

P34226

VPVPPPQL

11.76

-3.57

-5.05

TPTNSPSP

13.53

-2.10

-3.58

PVPPPQLH

14.03

-2.39

-3.87

P36102

DPFNAPIF

9.06

-3.89

-5.37

NVPPPMQP

12.53

-1.88

-3.36

LKYPRIYP

14.46

2.04

0.56

P53933

RPPPPPIP

9.87

-5.25

-6.73

PPIPSTQK

10.44

-3.80

-5.28

PPLPNRQL

10.64

-0.35

-1.83

Q04439

PPPPGMQN

5.18

-5.33

-6.81

PPPPSSKP

10.32

-4.19

-5.67

IPTPPQNR

11.25

-3.60

-5.08

Q12446

PPRRGPAP

6.73

-5.16

-6.64

PPPPAFLT

7.99

-4.41

-5.89

PPPPASLG

8.16

-4.51

-5.99

P39969

PPQPGSKK

4.15

-5.56

-7.04

SPRRAPKP

7.26

-5.44

-6.92

YPSPAQPP

10.65

-4.20

-5.68

P37370

PPPPGAFS

6.28

-4.75

-6.23

PPIPGAVP

6.55

-4.24

-5.72

PPIPGMGA

6.89

-3.78

-5.26

P53739

TPIMPSQN

11.67

-3.27

-4.75

RRRSPSTP

12.04

-2.20

-3.68

NASPASPP

12.83

-1.51

-2.99

P40563

MVNPGQLP

6.15

-5.12

-6.60

PPTPAGTP

8.59

-3.57

-5.05

PTPAGTPN

11.14

-1.89

-3.37

P40325

PPRPAANL

7.71

-4.82

-6.30

YVQPGDPR

8.91

-3.78

-5.26

QPRPPPRP

9.42

-5.85

-7.33

Q04195

RAPPPTNP

11.74

-3.57

-5.05

TPVLPTLP

12.44

-2.68

-4.16

LPTLPQNV

12.45

-2.78

-4.26

Q07555

LPLPASRP

5.56

-7.26

-8.74

KTKVPKLP

12.98

-3.04

-4.52

PASRPSLN

14.47

-2.17

-3.65

Q05080

LRQKPDKP

13.46

-3.77

-5.25

KPDKPRPI

14.57

-3.10

-4.58

RQKPDKPR

15.20

0.61

-0.87

 


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