ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BBC1_1TG0-12.PDB
Scoring matrix: BBC1_1TG0-12_mat
Uniprot code: P47068
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 14.52
Foldx random average score for Saccharomyces cerevisiae: 12.697

Available information for P47068 in MINT (Nov 2008):
Nš of interacting proteins: 45
 Proteins belonging to other specie: 0
Nš of interactions described: 64
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2180689
Proteins after random average filtering: 5078
 Total fragments: 847072
Proteins after disorder filtering: 3136
 Total fragments: 55847
Proteins after pattern filtering: 1513
 Total fragments: 8823
Proteins after MINT filtering: 28
 Total fragments: 506


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

14.52

0.67

0.00

Best peptides

WWRRPWWR

0.00

-3.49

-4.16

         
Interactors      
Q06604

KGPRMPSR

6.48

-5.51

-6.17

FEKGPRMP

8.82

-5.58

-6.25

NIPSSKPA

9.67

-2.85

-3.52

P24583

LPPQPRKH

9.80

-4.00

-4.67

PLPPQPRK

11.08

-4.63

-5.29

RANAPLPP

11.33

-1.33

-2.00

Q06625

PKQGPVTV

10.91

-1.95

-2.62

PLPKDAPK

11.13

-1.72

-2.38

GIPGTPRD

11.32

-4.22

-4.88

P19812

PRPRRIPP

5.30

-7.11

-7.78

RPRRIPPT

6.68

-7.16

-7.83

PIFRPGNI

7.54

-5.63

-6.29

P53182

SRRNPGKP

10.55

-3.55

-4.21

RRNPGKPP

11.32

-2.77

-3.44

P53169

YSPAQPSA

10.66

-2.70

-3.37

PIMPTLPP

10.90

-4.50

-5.17

IMPTLPPR

10.96

-2.51

-3.17

Q12043

PSRFPMDA

9.41

-3.35

-4.02

PGRFPLQP

10.01

-4.71

-5.38

GRFPLQPL

10.09

-2.81

-3.48

P40453

LRKRPPPP

5.62

-5.20

-5.87

RKRPPPPP

9.10

-3.35

-4.02

PEPPSWKP

9.19

-4.94

-5.61

P53971

ACPFLPSS

10.68

-2.63

-3.29

PGKCPPCL

11.14

-3.01

-3.67

CHPGKCPP

11.36

-2.60

-3.27

Q12168

QHPVPKPN

9.86

-3.07

-3.73

PYFPQFRS

10.14

-5.51

-6.17

RGPPPLPP

10.26

-3.71

-4.38

P27472

SVPGSPRD

10.91

-3.90

-4.56

P36006

SNKKPKNP

8.15

-4.29

-4.96

PPPMGQPK

10.36

-1.59

-2.25

GQPKDPKF

10.55

-4.00

-4.67

P32790

KPPRPTST

7.83

-5.02

-5.68

PIKPPRPT

8.21

-5.73

-6.40

PAMPARPT

9.83

-5.55

-6.21

Q06440

TPKVEPSK

10.65

-2.81

-3.48

RTPKVEPS

12.23

-1.25

-1.92

Q06412

KERRPPPP

5.06

-5.31

-5.97

ERRPPPPP

9.30

-3.57

-4.23

FTKPPPPL

9.76

-3.05

-3.71

P34226

EDFVPVPP

10.52

-2.81

-3.48

PVPPPQLH

10.77

-4.06

-4.72

FVPVPPPQ

10.87

-2.60

-3.27

P36102

KYPRIYPP

6.89

-3.99

-4.66

LKYPRIYP

10.17

-5.06

-5.72

NVPPPMQP

10.74

-5.02

-5.68

P53933

TRRRPPPP

5.00

-7.35

-8.02

RRRPPPPP

9.02

-3.61

-4.28

DLPMELPH

9.84

-2.63

-3.29

Q04439

SNARPSPP

9.36

-4.47

-5.13

HSKKPAPP

9.77

-2.72

-3.39

NARPSPPT

9.97

-3.08

-3.75

Q12446

PPRRGPAP

7.53

-5.78

-6.45

RNNRPVPP

7.78

-5.53

-6.20

PFPFPIPE

8.90

-3.03

-3.69

P39969

SPRRAPKP

6.36

-6.95

-7.62

VSPRRAPK

6.99

-3.45

-4.12

PRRAPKPP

7.78

-4.37

-5.04

P37370

PQNRPHMP

7.58

-4.14

-4.80

PKPRPFQN

7.75

-7.45

-8.12

QMPKPRPF

7.93

-5.27

-5.93

P53739

RRRSPSTP

9.74

-2.94

-3.61

PIMPSQNS

10.25

-4.49

-5.16

FFPQEPSP

10.49

-2.04

-2.71

P40563

PSERPKRR

6.33

-3.79

-4.46

RAPPPVPK

10.09

-2.79

-3.46

PPPVPKKP

10.56

-3.68

-4.35

P40325

SQPRPPPR

6.33

-6.05

-6.71

QPPRPPRP

7.36

-7.06

-7.72

QSRPHQRP

8.15

-4.52

-5.18

Q04195

SVPNPPNT

10.89

-2.77

-3.44

PQNVPIRT

10.96

-4.11

-4.78

RAPPPTNP

11.49

-3.38

-4.04

Q07555

KTKVPKLP

9.20

-3.49

-4.16

PLPASRPS

9.50

-3.28

-3.94

VPKLPLPA

9.96

-3.73

-4.39

Q05080

RQKPDKPR

8.53

-3.86

-4.53

PDKPRPIV

11.37

-4.27

-4.93

QKPDKPRP

11.72

-4.07

-4.74

 


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