ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BBC1_1FYN-27.PDB
Scoring matrix: BBC1_1FYN-27_mat
Uniprot code: P47068
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAAA
Foldx wt ligand score: 19.44
Foldx random average score for Saccharomyces cerevisiae: 16.205

Available information for P47068 in MINT (Nov 2008):
Nš of interacting proteins: 45
 Proteins belonging to other specie: 0
Nš of interactions described: 64
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2175611
Proteins after random average filtering: 5078
 Total fragments: 1094906
Proteins after disorder filtering: 3198
 Total fragments: 73903
Proteins after pattern filtering: 1607
 Total fragments: 14332
Proteins after MINT filtering: 28
 Total fragments: 735


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAAA

19.44

-4.71

0.00

Best peptides

RKRLFEMWK

0.00

-3.57

1.14

         
Interactors      
Q06604

PPPLPTRRD

8.76

-9.30

-4.59

EKPLLPTRP

9.12

-7.75

-3.04

KGPRMPSRG

9.17

-8.44

-3.73

P24583

RANAPLPPQ

9.77

-9.22

-4.51

NAPLPPQPR

10.09

-9.27

-4.56

APLPPQPRK

10.25

-9.36

-4.65

Q06625

VGIPGTPRD

9.57

-7.65

-2.94

VLTLPPIPL

10.37

-8.42

-3.71

LTLPPIPLP

12.30

-8.65

-3.94

P19812

RPRRIPPTD

9.39

-6.66

-1.95

PQNPPPILQ

11.88

-7.60

-2.89

PIFRPGNIF

12.77

-6.34

-1.63

P53182

SRRNPGKPP

10.02

-7.99

-3.28

SSRRNPGKP

14.32

-5.43

-0.72

P53169

MPTLPPRPY

8.94

-9.70

-4.99

PIMPTLPPR

12.87

-7.00

-2.29

IMPTLPPRP

13.53

-8.21

-3.50

Q12043

NPSRFPMDA

10.75

-5.54

-0.83

RFPLQPLPS

10.77

-9.89

-5.18

PGRFPLQPL

10.92

-7.81

-3.10

P40453

RKRPPPPPP

5.24

-10.35

-5.64

KVPEPPSWK

7.63

-8.43

-3.72

LRKRPPPPP

8.24

-10.74

-6.03

P53971

RKCHPGKCP

9.06

-8.40

-3.69

CPFLPSSLK

11.81

-7.84

-3.13

KCHPGKCPP

12.40

-7.96

-3.25

Q12168

RGPPPLPPR

8.74

-10.53

-5.82

GPPPLPPRA

10.21

-8.69

-3.98

KVQHPVPKP

10.87

-8.33

-3.62

P27472

LSVPGSPRD

9.18

-8.21

-3.50

PGSPRDLRS

15.98

-9.10

-4.39

VPGSPRDLR

16.09

-6.10

-1.39

P36006

IPPPPPPMG

9.98

-10.24

-5.53

IPIPPPPPP

11.04

-9.83

-5.12

MGQPKDPKF

11.21

-8.21

-3.50

P32790

EGPPPAMPA

11.02

-8.35

-3.64

PPIKPPRPT

11.89

-6.48

-1.77

EEGPPPAMP

11.99

-6.41

-1.70

Q06440

DRTPKVEPS

13.16

-6.10

-1.39

KDRTPKVEP

14.87

-7.17

-2.46

RTPKVEPSK

15.01

-6.26

-1.55

Q06412

RRPPPPPPL

7.56

-11.19

-6.48

ERRPPPPPP

8.19

-7.92

-3.21

KERRPPPPP

8.52

-9.41

-4.70

P34226

VPVPPPQLH

12.86

-8.07

-3.36

PVPPPQLHL

13.96

-6.54

-1.83

GSTPTNSPS

14.47

-6.69

-1.98

P36102

NNVPPPMQP

10.20

-7.81

-3.10

NLKYPRIYP

10.88

-8.96

-4.25

NVPPPMQPP

11.10

-8.65

-3.94

P53933

RRRPPPPPI

5.56

-10.73

-6.02

TRRRPPPPP

8.03

-7.58

-2.87

RRPPPPPIP

8.26

-12.57

-7.86

Q04439

KKPAPPPPG

10.09

-9.33

-4.62

NIPPPPPPP

10.35

-9.00

-4.29

ANIPPPPPP

10.59

-8.99

-4.28

Q12446

RNNRPVPPP

6.79

-9.03

-4.32

VPPPPPMRT

8.46

-10.13

-5.42

GVRLPAPPP

8.64

-8.55

-3.84

P39969

FKLLPPQPG

7.59

-10.82

-6.11

RAPKPPSYP

9.44

-8.65

-3.94

PRRAPKPPS

9.60

-7.73

-3.02

P37370

LAPLPPPPP

9.79

-9.96

-5.25

MPAPPPPPP

9.98

-11.06

-6.35

RPHMPSVRP

10.16

-10.28

-5.57

P53739

RRRSPSTPI

9.40

-7.98

-3.27

FPQEPSPKI

10.00

-7.49

-2.78

RSPSTPIMP

10.62

-8.08

-3.37

P40563

RRAPPPVPK

8.95

-10.85

-6.14

PSERPKRRA

9.50

-7.36

-2.65

KRRAPPPVP

10.07

-8.38

-3.67

P40325

YVQPGDPRL

7.05

-9.72

-5.01

QPRPPPRPQ

9.63

-9.04

-4.33

SQPRPPPRP

9.80

-8.21

-3.50

Q04195

RGNEPIQFP

6.41

-7.45

-2.74

RAPPPTNPD

10.56

-9.98

-5.27

HPSEPIIIN

11.18

-6.74

-2.03

Q07555

KLPLPASRP

8.26

-10.67

-5.96

VPKLPLPAS

12.06

-7.85

-3.14

TKVPKLPLP

12.87

-6.83

-2.12

Q05080

RQKPDKPRP

8.35

-9.15

-4.44

LRQKPDKPR

9.85

-8.69

-3.98

KPDKPRPIV

12.53

-8.16

-3.45

 


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