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Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BBC1_1FYN-19.PDB
Scoring matrix: BBC1_1FYN-19_mat
Uniprot code: P47068
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 18.77
Foldx random average score for Saccharomyces cerevisiae: 15.885

Available information for P47068 in MINT (Nov 2008):
Nº of interacting proteins: 45
 Proteins belonging to other specie: 0
Nº of interactions described: 64
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2175611
Proteins after random average filtering: 5078
 Total fragments: 988954
Proteins after disorder filtering: 3113
 Total fragments: 51036
Proteins after pattern filtering: 1429
 Total fragments: 5777
Proteins after MINT filtering: 27
 Total fragments: 240


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

18.77

0.19

0.00

Best peptides

MPFKRGRRR

0.00

-1.75

-1.94

         
Interactors      
Q06604

GPRMPSRGR

8.45

-6.40

-6.59

LPTRPNKAE

9.17

-4.56

-4.75

PPLPTRRDH

9.59

-4.96

-5.15

P24583

LPPQPRKHD

10.05

-5.33

-5.52

APLPPQPRK

10.08

-7.56

-7.75

PPQPRKHDK

11.40

-5.07

-5.26

Q06625

SVGIPGTPR

14.00

-6.21

-6.40

IPLPKDAPK

14.54

-4.86

-5.05

LPPIPLPKD

14.64

-5.12

-5.31

P19812

PIFRPGNIF

6.46

-10.63

-10.82

EPRPRRIPP

13.54

-7.26

-7.45

DHSPIFRPG

13.82

-4.43

-4.62

P53169

PIMPTLPPR

14.14

-8.04

-8.23

SPAQPSASL

14.32

-3.80

-3.99

VPIMPTLPP

15.00

-6.44

-6.63

Q12043

LFNPSRFPM

10.51

-7.20

-7.39

FPSTPLFEK

11.13

-3.13

-3.32

PSTSPQRSK

11.54

-4.40

-4.59

P40453

PDLPIRLRK

8.10

-7.99

-8.18

PPDLPIRLR

9.89

-8.00

-8.19

WKPPDLPIR

13.01

-6.83

-7.02

P53971

CPFLPSSLK

11.92

-5.35

-5.54

EKACPFLPS

12.25

-5.01

-5.20

PLDPNSCGQ

13.21

-3.81

-4.00

Q12168

PLPPRANVQ

10.27

-7.99

-8.18

PPPVPNRPG

10.45

-6.73

-6.92

DPYFPQFRS

11.71

-6.65

-6.84

P27472

VPGSPRDLR

9.15

-4.23

-4.42

PGSPRDLRS

9.76

-6.58

-6.77

PLSVPGSPR

10.44

-7.24

-7.43

P36006

PKNPGGLSG

10.18

-6.06

-6.25

KPKNPGGLS

10.77

-4.09

-4.28

MGQPKDPKF

10.86

-6.75

-6.94

P32790

APAPLDPFK

12.28

-5.21

-5.40

APLDPFKTG

13.48

-2.98

-3.17

PPAMPARPT

13.61

-6.86

-7.05

Q06440

DRTPKVEPS

15.38

-5.16

-5.35

Q06412

PKLPPLNTR

7.51

-7.71

-7.90

PPPPPLLYS

9.66

-6.38

-6.57

PKSPRDSSK

9.98

-4.74

-4.93

P34226

PVPPPQLHL

9.07

-8.70

-8.89

P36102

LKYPRIYPP

15.46

-7.14

-7.33

FNAPIFTPS

15.81

-3.80

-3.99

P53933

PPPLPNRQL

8.39

-8.64

-8.83

PPPIPSTQK

11.20

-6.99

-7.18

VAPPPLPNR

12.77

-7.06

-7.25

Q04439

APPPPGMQN

8.74

-4.91

-5.10

PPPPSSKPK

10.16

-5.88

-6.07

IPTPPQNRD

10.75

-6.90

-7.09

Q12446

PQLPNRNNR

8.81

-6.48

-6.67

LPQLPNRNN

9.52

-6.01

-6.20

PPPPPHRHV

10.32

-8.77

-8.96

P39969

LPPQPGSKK

7.69

-6.00

-6.19

PPQPGSKKG

10.02

-5.85

-6.04

PPKSPLLNN

11.62

-5.26

-5.45

P37370

PKVPQNRPH

8.57

-6.22

-6.41

PPPPPGAFS

10.71

-5.68

-5.87

PKPRPFQNK

11.24

-10.13

-10.32

P53739

PIMPSQNSN

11.79

-5.89

-6.08

TPIMPSQNS

14.23

-4.60

-4.79

PSTPIMPSQ

15.05

-4.45

-4.64

P40563

PSERPKRRA

10.41

-7.90

-8.09

PPTPAGTPN

11.28

-4.90

-5.09

PPPVPKKPS

11.74

-7.44

-7.63

P40325

LYVQPGDPR

8.67

-6.09

-6.28

PPRPAANLA

10.23

-5.86

-6.05

PPRPQQNPS

11.31

-6.20

-6.39

Q04195

PSEPIIINL

12.00

-6.00

-6.19

GNEPIQFPF

12.63

-7.01

-7.20

PQNVPIRTN

13.37

-5.63

-5.82

Q07555

PASRPSLNL

9.16

-8.67

-8.86

LPLPASRPS

10.72

-4.18

-4.37

KTKVPKLPL

13.38

-9.39

-9.58

Q05080

LRQKPDKPR

7.93

-7.49

-7.68

 


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