ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: ABP1_1OV32-9.PDB
Scoring matrix: ABP1_1OV32-9_mat
Uniprot code: P15891
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 17.75
Foldx random average score for Saccharomyces cerevisiae: 14.688

Available information for P15891 in MINT (Nov 2008):
Nš of interacting proteins: 39
 Proteins belonging to other specie: 0
Nš of interactions described: 88
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2181254
Proteins after random average filtering: 5078
 Total fragments: 964574
Proteins after disorder filtering: 3194
 Total fragments: 57741
Proteins after pattern filtering: 1545
 Total fragments: 9315
Proteins after MINT filtering: 27
 Total fragments: 340


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

17.75

4.51

0.00

Best peptides

RRWRHPRW

0.00

-4.58

-9.09

         
Interactors      
P09119

PTTSPVKK

11.96

-0.29

-4.80

TPTTSPVK

12.05

1.19

-3.32

VPLTPTTS

12.71

-0.08

-4.59

P43603

RFTAPTSP

12.01

-2.91

-7.42

APTSPSTS

13.66

0.47

-4.04

TAPTSPST

14.60

-0.62

-5.13

P53145

LPGQPPLI

11.01

-0.75

-5.26

EPLLPPLP

11.65

-0.62

-5.13

NEPLLPPL

11.67

-1.11

-5.62

P48562

MRQAPKRP

5.92

-4.56

-9.07

SPLNPYRP

9.51

-0.30

-4.81

GVAKPKKP

10.06

-3.64

-8.15

P17555

PPPRPKKP

7.84

-2.71

-7.22

RPKKPSTL

8.80

-2.55

-7.06

KSGPPPRP

9.00

-3.95

-8.46

P40494

RPPRPPPK

7.43

-4.59

-9.10

DKSRPPRP

7.64

-4.47

-8.98

RPPPKPLH

9.88

-2.49

-7.00

P08458

PKRKPPKL

7.36

-4.03

-8.54

NLPKRKPP

11.19

-1.95

-6.46

LPKRKPPK

11.37

-1.55

-6.06

P40325

QPPRPPRP

6.93

-2.89

-7.40

PWTYPPRF

9.17

-3.51

-8.02

RPPRPAAN

9.19

-3.53

-8.04

P40095

PPRSPNRP

9.58

0.13

-4.38

RIPVLPPP

10.02

-3.41

-7.92

PVLPPPRS

11.25

-3.76

-8.27

Q12168

PPPVPNRP

8.46

-2.86

-7.37

NRGPPPLP

8.77

-1.46

-5.97

PPPLPPRA

8.97

-3.50

-8.01

Q06449

NLPPPPQY

12.72

-2.55

-7.06

QQPFPPPS

13.34

-2.32

-6.83

YQQQPFPP

13.52

-2.05

-6.56

P32793

HGPTHPSN

12.93

-3.79

-8.30

GPTHPSNM

13.57

-0.83

-5.34

P32790

PPIKPPRP

7.64

-4.19

-8.70

APLDPFKT

8.58

0.10

-4.41

PPAMPARP

8.77

-3.04

-7.55

Q01389

KRSKPLPP

7.29

-3.68

-8.19

EPSTPSRP

8.22

-2.01

-6.52

KREAPKPP

9.01

-5.04

-9.55

P53974

KPKPPPKP

7.95

-2.21

-6.72

KPTPPPKP

8.02

-1.42

-5.93

LKPKPPPK

10.16

-3.91

-8.42

Q06836

KPPLSPSS

12.42

1.44

-3.07

SRGPLLPD

12.90

0.11

-4.40

PPLSPSSF

12.94

0.68

-3.83

Q05580

LPPPKPKV

10.52

-0.46

-4.97

PQLPPPKP

10.67

-3.28

-7.79

PPPKPKVQ

11.90

-2.73

-7.24

P53933

RRPPPPPI

7.33

-7.19

-11.70

RRRPPPPP

7.65

-6.16

-10.67

TRRRPPPP

8.54

-3.29

-7.80

Q04439

ARPSPPTA

10.38

-3.56

-8.07

KKPAPPPP

11.02

-4.38

-8.89

PPSSKPKE

11.10

-0.80

-5.31

Q08873

KKPRPPVK

8.27

-5.45

-9.96

KPRPPVKS

8.83

-2.38

-6.89

TKKPRPPV

13.69

-1.19

-5.70

P38885

APPSPENS

13.74

-0.15

-4.66

P50942

RPCPPIRR

6.79

-4.97

-9.48

KPEKPPVV

9.37

-1.17

-5.68

ASTKPEKP

9.44

-2.86

-7.37

P48415

GPKTKPRS

9.38

-5.54

-10.05

DFPAPPKL

10.49

-4.24

-8.75

RPPVIPLG

11.23

-1.31

-5.82

P40563

RRAPPPVP

7.69

-5.45

-9.96

TPKVPERP

8.31

-1.73

-6.24

PSERPKRR

8.37

-4.97

-9.48

P38822

PEVPPPRR

9.23

-6.09

-10.60

APEVPPPR

10.90

-2.10

-6.61

RGPAPEVP

11.60

-4.33

-8.84

Q12134

HQPVPSPM

11.93

-2.11

-6.62

QPVPSPMN

13.54

1.89

-2.62

P39743

NPLTSPVA

11.29

1.92

-2.59

 


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