ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: ABP1_1OV32-7.PDB
Scoring matrix: ABP1_1OV32-7_mat
Uniprot code: P15891
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 15.85
Foldx random average score for Saccharomyces cerevisiae: 14.384

Available information for P15891 in MINT (Nov 2008):
Nš of interacting proteins: 39
 Proteins belonging to other specie: 0
Nš of interactions described: 88
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2181254
Proteins after random average filtering: 5078
 Total fragments: 914962
Proteins after disorder filtering: 3098
 Total fragments: 45242
Proteins after pattern filtering: 1449
 Total fragments: 8496
Proteins after MINT filtering: 26
 Total fragments: 314


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

15.85

-0.85

0.00

Best peptides

MKKVRKRR

0.00

-5.18

-4.33

         
Interactors      
P09119

PTTSPVKK

12.30

-3.55

-2.70

MSAIPITP

12.70

-4.91

-4.06

P40325

QPPRPPRP

4.96

-7.35

-6.50

QPRPPPRP

5.44

-6.51

-5.66

PWTYPPRF

7.58

-5.58

-4.73

P53145

LPPLPGQP

9.71

-5.81

-4.96

LPGQPPLI

10.61

-5.58

-4.73

LLPPLPGQ

12.15

-3.17

-2.32

P48562

MRQAPKRP

3.75

-6.55

-5.70

SPLNPYRP

9.23

-4.82

-3.97

PPISAPRA

9.28

-4.38

-3.53

P17555

KSGPPPRP

6.42

-7.82

-6.97

RPKKPSTL

10.28

-5.74

-4.89

GPPPRPKK

10.33

-5.71

-4.86

P40494

DKSRPPRP

7.70

-3.96

-3.11

RPPPKPLH

8.37

-6.64

-5.79

RPPRPPPK

8.61

-6.32

-5.47

P08458

LPKRKPPK

9.41

-5.63

-4.78

PKRKPPKL

9.59

-3.72

-2.87

NLPKRKPP

11.71

-4.10

-3.25

P43603

RFTAPTSP

13.12

-3.78

-2.93

P40095

PVLPPPRS

8.37

-6.38

-5.53

PPRSPNRP

8.78

-5.02

-4.17

LPPPRSPN

11.19

-5.92

-5.07

Q12168

PPPLPPRA

6.93

-7.10

-6.25

PPPVPNRP

7.60

-6.72

-5.87

QHPVPKPN

10.10

-2.84

-1.99

Q06449

NLPPPPQY

9.43

-4.64

-3.79

QPQQQPQQ

10.14

-2.10

-1.25

QQPFPPPS

11.24

-4.04

-3.19

P32793

LGHGPTHP

14.13

-2.15

-1.30

GPTHPSNM

14.30

-3.17

-2.32

P32790

PPIKPPRP

7.54

-6.28

-5.43

PPAMPARP

8.04

-6.61

-5.76

LPPIKPPR

9.28

-6.56

-5.71

Q01389

SKPLPPQL

9.23

-2.71

-1.86

KREAPKPP

9.75

-5.61

-4.76

EPSTPSRP

9.90

-4.06

-3.21

P53974

LKPKPPPK

8.30

-5.70

-4.85

KPPPKPLL

9.09

-6.39

-5.54

KPKPPPKP

9.16

-6.20

-5.35

Q06836

KNKPPLSP

12.80

-4.48

-3.63

KPPLSPSS

12.93

-4.43

-3.58

NKPPLSPS

13.07

-1.94

-1.09

Q05580

QLPPPKPK

8.63

-4.95

-4.10

LPPPKPKV

9.49

-3.68

-2.83

LPQLPPPK

10.25

-5.37

-4.52

P53933

PPPLPNRQ

7.83

-7.07

-6.22

RRPPPPPI

9.60

-4.81

-3.96

RPPPPPIP

10.26

-5.56

-4.71

Q04439

KPKEPMFE

8.64

-4.63

-3.78

KKPAPPPP

9.81

-5.58

-4.73

PTPPQNRD

10.20

-4.67

-3.82

Q08873

KKPRPPVK

7.60

-6.11

-5.26

KPRPPVKS

9.10

-7.05

-6.20

FPVLGPQL

10.92

-3.20

-2.35

P38885

APPSPENS

14.06

-1.47

-0.62

P50942

RPCPPIRR

4.06

-9.29

-8.44

LPPVPALS

9.54

-5.90

-5.05

KPEKPPVV

9.85

-6.22

-5.37

P48415

GPKTKPRS

9.41

-5.83

-4.98

FPAPPKLG

9.93

-4.61

-3.76

LPMEPNHQ

10.75

-4.29

-3.44

P40563

PSERPKRR

5.53

-6.70

-5.85

TPKVPERP

7.86

-5.93

-5.08

PPPVPKKP

10.51

-5.70

-4.85

P38822

PEVPPPRR

7.03

-7.93

-7.08

APEVPPPR

10.63

-5.77

-4.92

RGPAPEVP

12.21

-3.99

-3.14

Q12134

QPVPSPMN

11.54

-3.57

-2.72

HQPVPSPM

11.67

-3.98

-3.13

 


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