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Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: ABP1_1OV32-21.PDB
Scoring matrix: ABP1_1OV32-21_mat
Uniprot code: P15891
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAGGAAAA
Foldx wt ligand score: 23.06
Foldx random average score for Saccharomyces cerevisiae: 18.738

Available information for P15891 in MINT (Nov 2008):
Nº of interacting proteins: 39
 Proteins belonging to other specie: 0
Nº of interactions described: 88
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2171098
Proteins after random average filtering: 5078
 Total fragments: 1179420
Proteins after disorder filtering: 2965
 Total fragments: 45302
Proteins after pattern filtering: 1107
 Total fragments: 2863
Proteins after MINT filtering: 23
 Total fragments: 78


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAGGAAAA

23.06

-0.28

0.00

Best peptides

EHRIGRPTRF

0.00

-2.89

-2.61

         
Interactors      
P09119

AQVPLTPTTS

15.52

-2.87

-2.59

LTPTTSPVKK

16.01

-3.57

-3.29

TPTTSPVKKS

18.66

-4.20

-3.92

P40325

YVQPGDPRLG

14.05

-4.57

-4.29

SRPHQRPSTM

15.19

-3.79

-3.51

PRPPPRPQQN

17.58

-2.66

-2.38

P48562

PYRPHHNMIN

13.54

-3.86

-3.58

PLNPYRPHHN

13.75

-3.88

-3.60

LNPYRPHHNM

15.38

-3.24

-2.96

P17555

PRPKKPSTLK

12.62

-3.72

-3.44

PKKPSTLKTK

12.89

-4.66

-4.38

PPRPKKPSTL

15.73

-3.02

-2.74

P40494

QPPNMMPVTH

16.60

-2.95

-2.67

PPNMMPVTHV

17.37

-3.54

-3.26

KPTLIPDNGN

18.31

-1.96

-1.68

P08458

LPKRKPPKLQ

12.97

-4.75

-4.47

P40095

PRSPNRPTLS

13.09

-4.19

-3.91

Q12168

PNRPGGTTNR

10.98

-3.44

-3.16

NDDPYFPQFR

15.21

-2.58

-2.30

GPPPLPPRAN

17.65

-2.45

-2.17

Q06449

QQPQQQPQQA

15.79

-1.94

-1.66

P32793

GHGPTHPSNM

15.51

-2.75

-2.47

P32790

PPRPTSTTSV

16.42

-2.62

-2.34

PIKPPRPTST

17.09

-2.27

-1.99

APAPLDPFKT

17.69

-3.39

-3.11

Q01389

RSKPLPPQLL

11.83

-4.35

-4.07

IASPTSPKSL

15.44

-2.27

-1.99

QFPNLTPNST

17.41

-4.05

-3.77

P53974

TPPPKPSHLK

15.48

-4.24

-3.96

Q06836

PLLPDDANII

16.21

-2.26

-1.98

NKPPLSPSSF

16.73

-2.74

-2.46

Q05580

LPPPKPKVQI

15.54

-3.70

-3.42

P53933

VSYPGNPTSR

11.74

-2.85

-2.57

PPPPIPSTQK

15.16

-4.07

-3.79

APPPLPNRQL

15.59

-4.56

-4.28

Q04439

SSKPKEPMFE

13.97

-2.86

-2.58

NNIPTPPQNR

13.98

-3.53

-3.25

PPPPGMQNKA

17.02

-3.11

-2.83

Q08873

TKKPRPPVKS

14.48

-3.93

-3.65

P38885

AAPPSPENSH

17.73

-0.73

-0.45

P50942

VPRPCPPIRR

11.02

-6.96

-6.68

PRPCPPIRRK

16.46

-4.98

-4.70

PPPPTSRHNK

16.58

-3.25

-2.97

P48415

NLLPMEPNHQ

14.16

-3.02

-2.74

IVSPKPPVVK

14.48

-3.44

-3.16

NYSPYVPQST

15.49

-2.17

-1.89

P38822

APEVPPPRRS

18.65

-4.61

-4.33

Q12134

QPVPSPMNSQ

16.81

-0.43

-0.15

 


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