ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: ABP1_1JO8-7.PDB
Scoring matrix: ABP1_1JO8-7_mat
Uniprot code: P15891
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 13.55
Foldx random average score for Saccharomyces cerevisiae: 10.858

Available information for P15891 in MINT (Nov 2008):
Nš of interacting proteins: 39
 Proteins belonging to other specie: 0
Nš of interactions described: 88
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2181254
Proteins after random average filtering: 5078
 Total fragments: 958367
Proteins after disorder filtering: 3121
 Total fragments: 49338
Proteins after pattern filtering: 1437
 Total fragments: 8231
Proteins after MINT filtering: 24
 Total fragments: 312


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

13.55

-1.27

0.00

Best peptides

KMKRRPRK

0.00

-6.85

-5.58

         
Interactors      
P09119

PTTSPVKK

8.92

-4.26

-2.99

MSAIPITP

9.84

-4.29

-3.02

TPTTSPVK

10.78

-2.18

-0.91

P40325

QPPRPPRP

4.90

-5.80

-4.53

QPRPPPRP

6.07

-6.61

-5.34

RPPPRPQQ

6.48

-5.93

-4.66

P53145

LPGQPPLI

7.87

-5.05

-3.78

NEPLLPPL

9.07

-3.50

-2.23

LLPPLPGQ

9.28

-3.24

-1.97

P48562

KPPISAPR

5.46

-3.96

-2.69

KQPQSPLS

6.06

-2.54

-1.27

MRQAPKRP

6.90

-5.95

-4.68

P17555

KSGPPPRP

5.36

-6.12

-4.85

GPPPRPKK

7.25

-5.01

-3.74

RPKKPSTL

7.47

-3.67

-2.40

P40494

RPPRPPPK

4.90

-6.86

-5.59

RPPPKPLH

5.81

-5.38

-4.11

DKSRPPRP

5.91

-7.04

-5.77

P08458

LPKRKPPK

6.15

-6.26

-4.99

PKRKPPKL

7.36

-6.21

-4.94

TNLPKRKP

9.35

-4.10

-2.83

P40095

PVLPPPRS

7.71

-6.63

-5.36

PPPRSPNR

7.80

-4.76

-3.49

PPRSPNRP

8.26

-6.00

-4.73

Q12168

PPPLPPRA

5.74

-8.33

-7.06

DPYFPQFR

7.12

-5.79

-4.52

PPPVPNRP

7.56

-7.01

-5.74

Q06449

QQPFPPPS

8.20

-3.76

-2.49

QPQQQPQQ

8.63

-3.57

-2.30

QQPQQQPQ

8.86

-2.96

-1.69

P32793

PTHPSNMS

10.33

-2.81

-1.54

GPTHPSNM

10.85

-3.48

-2.21

P32790

LPPIKPPR

6.53

-5.70

-4.43

PPIKPPRP

6.85

-6.38

-5.11

KPPRPTST

6.91

-4.21

-2.94

P53974

KPPPKPLL

5.44

-4.34

-3.07

KPKPPPKP

6.17

-4.71

-3.44

LKPKPPPK

6.73

-4.98

-3.71

Q01389

KPLPPQLL

6.70

-4.73

-3.46

RSKPLPPQ

7.31

-3.93

-2.66

KRSKPLPP

7.58

-4.46

-3.19

Q05580

QLPPPKPK

7.18

-3.65

-2.38

LPPPKPKV

7.41

-4.93

-3.66

LPQLPPPK

7.45

-5.21

-3.94

P53933

PPPLPNRQ

5.52

-7.93

-6.66

RRPPPPPI

7.41

-5.29

-4.02

RPPPPPIP

7.84

-4.88

-3.61

Q04439

KPKEPMFE

7.02

-3.17

-1.90

KPAPPPPG

7.43

-4.30

-3.03

APPPPGMQ

7.67

-4.76

-3.49

Q08873

KKPRPPVK

4.68

-6.02

-4.75

KPRPPVKS

5.98

-5.24

-3.97

TKKPRPPV

9.75

-3.16

-1.89

Q06836

KPPLSPSS

7.61

-2.66

-1.39

KNKPPLSP

8.20

-2.77

-1.50

PLSPSSFI

9.45

-1.97

-0.70

P50942

RPCPPIRR

4.43

-7.94

-6.67

KPEKPPVV

6.64

-4.52

-3.25

KPLPPVPA

7.71

-3.66

-2.39

P48415

VPPVSPYG

8.13

-3.16

-1.89

VSPKPPVV

8.16

-4.48

-3.21

GPKTKPRS

8.24

-6.31

-5.04

P40563

PSERPKRR

4.84

-7.30

-6.03

RAPPPVPK

7.28

-4.35

-3.08

TPKVPERP

7.50

-6.32

-5.05

P38822

PEVPPPRR

5.31

-7.62

-6.35

APEVPPPR

8.31

-5.84

-4.57

RGPAPEVP

10.58

-4.64

-3.37

Q12134

QPVPSPMN

8.07

-3.39

-2.12

HQPVPSPM

8.85

-2.94

-1.67

 


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