ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: ABP1_1JO8-3.PDB
Scoring matrix: ABP1_1JO8-3_mat
Uniprot code: P15891
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 20.85
Foldx random average score for Saccharomyces cerevisiae: 18.474

Available information for P15891 in MINT (Nov 2008):
Nš of interacting proteins: 39
 Proteins belonging to other specie: 0
Nš of interactions described: 88
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2171098
Proteins after random average filtering: 5078
 Total fragments: 983348
Proteins after disorder filtering: 3118
 Total fragments: 56317
Proteins after pattern filtering: 1540
 Total fragments: 9710
Proteins after MINT filtering: 26
 Total fragments: 305


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

20.85

2.01

0.00

Best peptides

KIKRRGRPRY

0.00

-5.83

-7.84

         
Interactors      
P09119

TPTTSPVKKS

16.82

-1.70

-3.71

PTTSPVKKSY

18.42

-2.09

-4.10

P43603

QGRFTAPTSP

16.65

-3.97

-5.98

P53145

LPPLPGQPPL

15.94

-3.72

-5.73

EPLLPPLPGQ

17.01

-2.32

-4.33

LPGQPPLINI

17.11

-3.99

-6.00

P48562

NPYRPHHNMI

9.63

-4.88

-6.89

FPRGPMHPNN

11.61

-5.78

-7.79

PPISAPRAPY

12.32

-6.99

-9.00

P17555

KSGPPPRPKK

12.26

-9.69

-11.70

GSKSGPPPRP

12.79

-6.41

-8.42

RPKKPSTLKT

13.45

-4.88

-6.89

P40494

KSRPPRPPPK

12.80

-7.40

-9.41

GKDKSRPPRP

14.10

-4.40

-6.41

PPRPPPKPLH

14.20

-7.74

-9.75

P08458

LPKRKPPKLQ

10.85

-8.95

-10.96

MTNLPKRKPP

12.18

-9.98

-11.99

VMTNLPKRKP

13.36

-4.67

-6.68

P40325

LPWTYPPRFY

10.84

-3.48

-5.49

NPSLPWTYPP

12.55

-4.31

-6.32

QPRPPPRPQQ

13.13

-6.76

-8.77

P40095

IPVLPPPRSP

13.55

-5.56

-7.57

PPSSTFPDSP

14.05

-5.58

-7.59

NRIPVLPPPR

14.16

-4.34

-6.35

Q12168

VPNRPGGTTN

13.17

-4.30

-6.31

TTNRGPPPLP

13.33

-8.25

-10.26

TNRGPPPLPP

14.07

-5.32

-7.33

Q06449

PSNLPPPPQY

12.80

-4.14

-6.15

QPFPPPSTNY

14.55

-4.54

-6.55

GPSNLPPPPQ

15.78

-3.69

-5.70

P32793

YSLGHGPTHP

11.71

-4.61

-6.62

GHGPTHPSNM

17.80

-6.20

-8.21

SLGHGPTHPS

18.45

-1.67

-3.68

P32790

PPIKPPRPTS

14.26

-8.01

-10.02

PPAMPARPTA

15.32

-8.48

-10.49

PIKPPRPTST

15.86

-5.04

-7.05

P53974

KPSHLKPKPP

9.78

-6.24

-8.25

KPKPPPKPLL

11.80

-7.29

-9.30

KTKPTPPPKP

11.96

-6.33

-8.34

Q01389

KRSKPLPPQL

11.52

-6.47

-8.48

APKREAPKPP

12.29

-7.53

-9.54

GSGRRYPQTP

13.41

-7.23

-9.24

Q05580

LPQLPPPKPK

14.96

-5.04

-7.05

KSLNLPQLPP

15.31

-3.97

-5.98

LKSLNLPQLP

15.38

-5.31

-7.32

P53933

RTRRRPPPPP

8.90

-9.38

-11.39

VRTRRRPPPP

12.51

-9.31

-11.32

TRRRPPPPPI

12.56

-6.80

-8.81

Q04439

HSKKPAPPPP

12.32

-5.67

-7.68

PSSKPKEPMF

13.04

-3.91

-5.92

RHSKKPAPPP

13.30

-6.45

-8.46

Q08873

STKKPRPPVK

12.60

-5.67

-7.68

LSTKKPRPPV

12.93

-7.60

-9.61

KPRPPVKSKP

15.00

-5.65

-7.66

Q06836

PMGSRGPLLP

11.63

-7.32

-9.33

GSRGPLLPDD

14.37

-3.62

-5.63

TAKNKPPLSP

15.45

-5.00

-7.01

P50942

VPRPCPPIRR

11.79

-7.23

-9.24

NGKIVPRPCP

13.61

-5.55

-7.56

KIVPRPCPPI

13.69

-4.35

-6.36

P48415

PPTGILPLAP

12.61

-5.89

-7.90

GPKTKPRSGP

12.67

-7.04

-9.05

NIVSPKPPVV

13.09

-3.46

-5.47

P40563

PSERPKRRAP

12.48

-7.40

-9.41

PKRRAPPPVP

12.69

-7.88

-9.89

KRRAPPPVPK

12.96

-6.53

-8.54

P38822

APEVPPPRRS

15.56

-3.64

-5.65

Q12134

RSTHQPVPSP

14.33

-3.79

-5.80

QPVPSPMNSQ

18.12

-3.19

-5.20

P39743

PAYSNPLTSP

17.29

-3.30

-5.31

 


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