ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: ABP1_1JO8-28.PDB
Scoring matrix: ABP1_1JO8-28_mat
Uniprot code: P15891
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 28.06
Foldx random average score for Saccharomyces cerevisiae: 23.973

Available information for P15891 in MINT (Nov 2008):
Nš of interacting proteins: 39
 Proteins belonging to other specie: 0
Nš of interactions described: 88
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2171098
Proteins after random average filtering: 5078
 Total fragments: 1004448
Proteins after disorder filtering: 2871
 Total fragments: 38743
Proteins after pattern filtering: 1365
 Total fragments: 6617
Proteins after MINT filtering: 27
 Total fragments: 218


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

28.06

-0.44

0.00

Best peptides

RIRRHRRRRR

0.00

-13.09

-12.65

         
Interactors      
P09119

LTPTTSPVKK

19.62

-3.72

-3.28

PTTSPVKKSY

21.43

-3.71

-3.27

P43603

RFTAPTSPST

20.71

-3.90

-3.46

P53145

LPGQPPLINI

19.73

-7.63

-7.19

EPLLPPLPGQ

20.83

-5.01

-4.57

P48562

NPYRPHHNMI

16.13

-7.64

-7.20

LNPYRPHHNM

17.90

-9.54

-9.10

APKRPDADVA

18.80

-9.54

-9.10

P17555

PPPRPKKPST

14.95

-10.36

-9.92

KSGPPPRPKK

15.78

-8.53

-8.09

RPKKPSTLKT

17.48

-9.97

-9.53

P40494

RPPRPPPKPL

15.97

-9.96

-9.52

PPRPPPKPLH

21.42

-7.95

-7.51

KSRPPRPPPK

21.49

-6.01

-5.57

P08458

LPKRKPPKLQ

13.13

-11.13

-10.69

NLPKRKPPKL

19.94

-8.79

-8.35

PKRKPPKLQG

20.60

-8.10

-7.66

P40325

RPPRPAANLA

14.36

-11.35

-10.91

QPPRPPRPAA

14.69

-11.57

-11.13

QPRPPPRPQQ

17.40

-8.21

-7.77

P40095

RIPVLPPPRS

16.36

-9.51

-9.07

VLPPPRSPNR

19.60

-9.77

-9.33

PPRSPNRPTL

20.07

-5.07

-4.63

Q12168

RGPPPLPPRA

17.37

-6.01

-5.57

DDPYFPQFRS

19.72

-6.80

-6.36

PPPLPPRANV

20.20

-6.80

-6.36

Q06449

YQQPQQQPQQ

20.67

-6.22

-5.78

QQQPFPPPST

21.57

-4.68

-4.24

QPFPPPSTNY

22.65

-6.58

-6.14

P32793

HGPTHPSNMS

23.30

-3.59

-3.15

P32790

KPPRPTSTTS

17.67

-8.55

-8.11

PPAMPARPTA

19.65

-8.48

-8.04

EGPPPAMPAR

21.30

-8.64

-8.20

Q01389

SPSYPSIFRR

15.28

-9.09

-8.65

KRSKPLPPQL

19.25

-7.26

-6.82

REAPKPPANT

19.27

-6.34

-5.90

P53974

KPKPPPKPLL

18.57

-8.85

-8.41

KPPPKPLLLA

18.99

-8.35

-7.91

KPTPPPKPSH

19.93

-7.69

-7.25

Q06836

KPPLSPSSFI

22.51

-5.08

-4.64

Q05580

LPPPKPKVQI

19.38

-8.30

-7.86

QLPPPKPKVQ

20.82

-7.58

-7.14

LPQLPPPKPK

22.27

-6.79

-6.35

P53933

RVAPPPLPNR

14.32

-12.76

-12.32

RPPPPPIPST

17.36

-8.78

-8.34

VAPPPLPNRQ

19.13

-7.10

-6.66

Q04439

RPSPPTAATR

16.96

-9.08

-8.64

NIPTPPQNRD

19.39

-8.24

-7.80

SNARPSPPTA

19.43

-9.13

-8.69

Q08873

KKPRPPVKSK

12.05

-9.05

-8.61

STKKPRPPVK

18.47

-5.98

-5.54

PVLGPQLSTK

21.23

-6.39

-5.95

P38885

APPSPENSHQ

19.36

-6.38

-5.94

P50942

IVPRPCPPIR

12.81

-13.67

-13.23

PRPCPPIRRK

15.78

-9.54

-9.10

VPRPCPPIRR

16.42

-10.82

-10.38

P48415

PPPPPIVKRK

16.32

-9.16

-8.72

RPPVIPLGTQ

16.38

-8.24

-7.80

APPPPPIVKR

17.31

-7.49

-7.05

P40563

RRAPPPVPKK

15.95

-8.68

-8.24

PAGTPNVPTR

21.26

-5.89

-5.45

SEVTPKVPER

21.30

-3.75

-3.31

P38822

PAPEVPPPRR

18.32

-8.86

-8.42

APEVPPPRRS

19.68

-8.07

-7.63

Q12134

PVPSPMNSQT

21.43

-4.88

-4.44

QPVPSPMNSQ

22.12

-5.30

-4.86

STHQPVPSPM

23.12

-4.76

-4.32

P39743

YSNPLTSPVA

22.32

-3.84

-3.40

 


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