ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: ABP1_1JO8-20.PDB
Scoring matrix: ABP1_1JO8-20_mat
Uniprot code: P15891
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 19.23
Foldx random average score for Saccharomyces cerevisiae: 18.148

Available information for P15891 in MINT (Nov 2008):
Nš of interacting proteins: 39
 Proteins belonging to other specie: 0
Nš of interactions described: 88
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2176176
Proteins after random average filtering: 5078
 Total fragments: 923710
Proteins after disorder filtering: 3121
 Total fragments: 58722
Proteins after pattern filtering: 1392
 Total fragments: 5887
Proteins after MINT filtering: 25
 Total fragments: 175


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

19.23

1.81

0.00

Best peptides

HRPKNGRSF

0.00

-5.08

-6.89

         
Interactors      
P09119

LTPTTSPVK

17.82

-2.85

-4.67

P40325

PRPPPRPQQ

12.13

-4.78

-6.60

PRPQQNPSL

13.14

-3.10

-4.92

RPPRPAANL

13.25

-8.24

-10.06

P53145

PLLPPLPGQ

16.93

-3.79

-5.61

P48562

NPYRPHHNM

11.71

-8.35

-10.16

PRPPSSNSQ

11.89

-2.77

-4.59

GQFPRGPMH

12.73

-4.12

-5.94

P17555

RPKKPSTLK

10.84

-6.68

-8.49

PPRPKKPST

13.91

-3.79

-5.61

SGPPPRPKK

13.92

-4.52

-6.33

P40494

PRPPPKPLH

12.90

-4.65

-6.46

NQPPNMMPV

16.12

-3.87

-5.69

P08458

NLPKRKPPK

11.99

-7.32

-9.13

PITNPSSSS

17.27

-0.77

-2.59

VTPITNPSS

17.63

0.48

-1.34

P43603

FTAPTSPST

14.37

-1.88

-3.69

APTSPSTSS

15.92

-1.32

-3.13

P40095

PRSPNRPTL

11.28

-5.83

-7.64

LPPPRSPNR

12.27

-5.92

-7.73

FPDSPSSSS

14.27

-2.00

-3.81

Q12168

NDDPYFPQF

12.41

-3.60

-5.42

VPNRPGGTT

13.79

-4.82

-6.63

RGPPPLPPR

14.53

-6.02

-7.83

Q06449

PFPPPSTNY

15.73

-4.44

-6.26

QQPQQQPQQ

16.88

-2.55

-4.37

YQQPQQQPQ

18.10

-4.09

-5.90

P32793

GHGPTHPSN

14.56

-2.09

-3.90

PTHPSNMSN

15.55

-2.01

-3.82

GPTHPSNMS

17.56

-2.72

-4.54

P32790

APAPLDPFK

14.71

-2.31

-4.13

PIKPPRPTS

15.09

-5.36

-7.18

PPAMPARPT

15.41

-3.76

-5.57

Q01389

RPVPPDSSY

9.99

-5.85

-7.66

RRYPQTPSY

11.55

-4.10

-5.91

YPQTPSYYY

11.71

-4.75

-6.56

P53974

PTPPPKPSH

13.01

-3.87

-5.69

PPPKPSHLK

13.28

-4.75

-6.56

PKPPPKPLL

14.37

-5.31

-7.13

Q06836

NKPPLSPSS

13.39

-1.55

-3.37

KNKPPLSPS

17.13

-1.07

-2.88

Q05580

QLPPPKPKV

15.29

-6.78

-8.60

PPPKPKVQI

15.92

-5.73

-7.54

P53933

PPPIPSTQK

15.72

-1.71

-3.52

PPPPPIPST

16.04

-2.18

-4.00

VAPPPLPNR

16.19

-4.13

-5.95

Q04439

APPPPGMQN

12.89

-3.01

-4.82

SSKPKEPMF

13.50

-4.16

-5.97

PSSKPKEPM

14.44

-2.95

-4.77

Q08873

KPRPPVKSK

12.34

-6.51

-8.32

STKKPRPPV

16.21

-4.47

-6.29

P38885

APPSPENSH

14.43

-2.30

-4.12

PPSPENSHQ

17.57

-3.12

-4.94

P50942

RPCPPIRRK

10.35

-7.15

-8.96

PCPPIRRKS

12.57

-4.42

-6.23

LPPVPALSL

13.69

-5.84

-7.65

P48415

FPAPPKLGT

14.76

-4.01

-5.82

PPPPPIVKR

14.98

-4.51

-6.32

APPKPKSTD

15.16

-4.69

-6.51

P40563

PSERPKRRA

12.59

-3.08

-4.89

NSQPQGPSD

13.92

-1.45

-3.26

RAPPPVPKK

15.24

-5.35

-7.16

Q12134

HQPVPSPMN

15.46

-2.36

-4.17

PVPSPMNSQ

15.66

-1.36

-3.17

 


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