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Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: ABP1_1JO8-11.PDB
Scoring matrix: ABP1_1JO8-11_mat
Uniprot code: P15891
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 16.34
Foldx random average score for Saccharomyces cerevisiae: 12.837

Available information for P15891 in MINT (Nov 2008):
Nº of interacting proteins: 39
 Proteins belonging to other specie: 0
Nº of interactions described: 88
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2186332
Proteins after random average filtering: 5078
 Total fragments: 897427
Proteins after disorder filtering: 3218
 Total fragments: 60467
Proteins after pattern filtering: 1543
 Total fragments: 8287
Proteins after MINT filtering: 27
 Total fragments: 292


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

16.34

-0.41

0.00

Best peptides

YRPIHRR

0.00

-6.68

-6.27

         
Interactors      
P09119

VPLTPTT

11.63

-0.95

-0.54

PTTSPVK

11.97

-1.77

-1.36

P43603

APTSPST

12.59

-1.72

-1.31

P53145

LPPLPGQ

10.87

-4.10

-3.69

LPGQPPL

11.15

-3.99

-3.58

NEPLLPP

11.60

-3.20

-2.79

P48562

RGPMHPN

7.53

-4.25

-3.84

NPYRPHH

8.23

-8.95

-8.54

SPLNPYR

8.30

-3.48

-3.07

P17555

PPPRPKK

8.50

-4.92

-4.51

RPKKPST

9.85

-4.19

-3.78

PRPKKPS

10.18

-3.81

-3.40

P40494

RPPRPPP

7.79

-10.20

-9.79

RPPPKPL

9.08

-4.44

-4.03

PPPKPLH

9.52

-4.60

-4.19

P08458

NLPKRKP

8.85

-6.45

-6.04

PKRKPPK

9.54

-5.36

-4.95

LPKRKPP

9.88

-7.73

-7.32

P40325

QPPRPPR

6.28

-5.10

-4.69

QPRPPPR

7.87

-5.16

-4.75

PWTYPPR

8.26

-3.94

-3.53

P40095

PPRSPNR

7.89

-3.90

-3.49

PVLPPPR

8.80

-2.99

-2.58

RIPVLPP

8.85

-5.09

-4.68

Q12168

PPPVPNR

6.76

-5.08

-4.67

PPPLPPR

7.57

-4.89

-4.48

DDPYFPQ

9.64

-0.86

-0.45

Q06449

NLPPPPQ

9.39

-4.37

-3.96

LPPPPQY

11.57

-3.21

-2.80

QQPFPPP

11.83

-3.30

-2.89

P32793

HGPTHPS

9.84

-3.46

-3.05

GPTHPSN

11.29

-3.18

-2.77

P32790

PPIKPPR

6.88

-4.99

-4.58

PPAMPAR

7.41

-4.47

-4.06

LPPIKPP

9.52

-4.86

-4.45

Q01389

EPSTPSR

7.38

-3.74

-3.33

YPQTPSY

8.22

-4.77

-4.36

SRPVPPD

10.35

-2.62

-2.21

P53974

KPKPPPK

8.85

-4.50

-4.09

KPTPPPK

9.20

-5.00

-4.59

PPPKPSH

9.24

-4.60

-4.19

Q06836

NKPPLSP

11.43

-3.12

-2.71

SRGPLLP

11.86

-2.30

-1.89

PLSPSSF

12.40

-3.02

-2.61

Q05580

LPPPKPK

9.58

-3.99

-3.58

NLPQLPP

9.73

-4.79

-4.38

QLPPPKP

10.87

-4.74

-4.33

P53933

PPPLPNR

8.14

-4.51

-4.10

RRPPPPP

8.26

-5.39

-4.98

RRRPPPP

8.47

-5.46

-5.05

Q04439

NIPTPPQ

9.08

-3.12

-2.71

KPKEPMF

9.23

-4.16

-3.75

PPSSKPK

9.88

-3.17

-2.76

Q08873

KPRPPVK

9.46

-3.83

-3.42

KKPRPPV

9.94

-7.60

-7.19

FPVLGPQ

11.81

-3.22

-2.81

P38885

APPSPEN

11.89

-1.93

-1.52

P50942

RPCPPIR

6.75

-5.25

-4.84

PCPPIRR

9.99

-4.17

-3.76

PRPCPPI

9.99

-3.36

-2.95

P48415

GPKTKPR

6.61

-4.44

-4.03

FPAPPKL

9.49

-3.71

-3.30

MEPNHQP

9.61

-3.06

-2.65

P40563

TPNVPTR

7.46

-3.71

-3.30

PSERPKR

7.49

-3.22

-2.81

TPKVPER

8.33

-3.79

-3.38

P38822

PEVPPPR

8.99

-3.33

-2.92

APEVPPP

9.99

-4.05

-3.64

PTTTPGS

12.83

-1.54

-1.13

Q12134

HQPVPSP

10.30

-3.45

-3.04

PVPSPMN

11.59

-2.56

-2.15

P39743

PLTSPVA

12.58

-2.50

-2.09

NPLTSPV

12.76

-1.10

-0.69

 


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