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Matrix information:
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ADAN-name: 3GBQ2.PDB
Scoring matrix: 3GBQ2_mat
Uniprot code: Q60631
Genome source: Mus musculus
Wild-type ligand: VPPPVPPRRR
Foldx wt ligand score: 0.97
Foldx random average score for Mus musculus: 9.379 Available information for Q60631 in MINT (Nov 2008):
Nš of interacting proteins: 32
Proteins belonging to other specie: 6
Nš of interactions described: 55
Interactions with other species: 12
Genome scanning information:
Subcellular location: True
Proteins in genome Mus musculus: 58346
Proteins located in other compartments: 13502
Proteins considered as fragments or having non-standard amino acids: 13900
Total scanned proteins: 30944
Total fragments: 13390911
Proteins after random average filtering: 30939
Total fragments: 6753015
Proteins after disorder filtering: 22460
Total fragments: 682364
Proteins after pattern filtering: 16072
Total fragments: 202914
Proteins after MINT filtering: 13
Total fragments: 342
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
VPPPVPPRRR |
0.97
|
-13.71 |
0.00 |
| Best peptides |
IMVEMPRRGH |
0.00
|
-8.73 |
4.98 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q62245 |
VPPPVPPRRR |
0.97
|
-13.32 |
0.39 |
|
SPPAIPPRQP |
1.42
|
-13.11 |
0.60 |
|
PPPVPPRRRP |
1.51
|
-13.11 |
0.60 |
| P04925 |
NQWNKPSKPK |
8.11
|
-9.01 |
4.70 |
| Q923U0 |
RLPPLPSSHP |
4.55
|
-9.09 |
4.62 |
|
LSPIVPVPTP |
4.56
|
-7.58 |
6.13 |
|
ISPNRPTSVP |
4.77
|
-6.73 |
6.98 |
| Q02384 |
DPPAIPPRQP |
1.42
|
-12.81 |
0.90 |
|
PAPPVPPRQN |
1.77
|
-13.31 |
0.40 |
|
IPPPLPPRKK |
1.85
|
-12.85 |
0.86 |
| Q91ZZ2 |
SPPALPPKKR |
2.02
|
-10.32 |
3.39 |
|
PPPALPPKQR |
2.25
|
-9.78 |
3.93 |
|
PPALPPKKRQ |
2.87
|
-8.95 |
4.76 |
| Q60992 |
PPTGRPPSRE |
4.70
|
-9.26 |
4.45 |
|
ADVDAPGAGP |
5.44
|
-4.93 |
8.78 |
|
HGNPAPPGKP |
5.47
|
-5.16 |
8.55 |
| O35716 |
AAPVRPRPCP |
3.32
|
-7.90 |
5.81 |
|
PCPAVPAPAP |
3.88
|
-7.59 |
6.12 |
|
PAVPAPAPGD |
4.45
|
-6.44 |
7.27 |
| Q80U87 |
VHMYPPEMAP |
3.72
|
-8.58 |
5.13 |
|
LEEPVPSKLP |
4.19
|
-7.51 |
6.20 |
|
APPSTPPTHK |
4.29
|
-7.95 |
5.76 |
| Q9EQ32 |
RPPRVPPRAA |
1.71
|
-13.08 |
0.63 |
|
VPVPRPEASA |
3.34
|
-8.18 |
5.53 |
|
GPPPPPDNEP |
3.65
|
-9.96 |
3.75 |
| Q9Z1S8 |
PRPPKPSQAE |
3.87
|
-9.35 |
4.36 |
|
PPPRPPKPSQ |
4.50
|
-8.78 |
4.93 |
|
EENYVPMQNP |
5.00
|
-6.33 |
7.38 |
| P27870 |
IPPPPGAFGP |
5.17
|
-7.32 |
6.39 |
|
YGIPPPPGAF |
5.50
|
-6.06 |
7.65 |
|
YYGIPPPPGA |
5.99
|
-5.59 |
8.12 |
| Q62077 |
DCWDGPDGMP |
5.31
|
-4.61 |
9.10 |
|
DGPDGMPVIY |
8.46
|
-4.28 |
9.43 |
| Q9QYY0 |
SSPKTPPRRP |
2.87
|
-10.01 |
3.70 |
|
PPKPHPTHDR |
3.54
|
-7.96 |
5.75 |
|
NPNSPPRQHS |
3.58
|
-9.01 |
4.70 |
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