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Matrix information:
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ADAN-name: 3B762.PDB
Scoring matrix: 3B762_mat
Uniprot code: Q8TBB1
Genome source: Homo sapiens
Wild-type ligand: EGSIV
Foldx wt ligand score: 3.11
Foldx random average score for Homo sapiens: 15.337 Available information for Q8TBB1 in MINT (Nov 2008):
Nš of interacting proteins: 44
Proteins belonging to other specie: 0
Nš of interactions described: 50
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 7744
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 40317
Total fragments: 18411866
Proteins after random average filtering: 40314
Total fragments: 9881794
Proteins after disorder filtering: 32755
Total fragments: 1494799
Proteins after pattern filtering: 24932
Total fragments: 135478
Proteins after MINT filtering: 22
Total fragments: 77
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
EGSIV |
3.11
|
-8.04 |
0.00 |
| Best peptides |
WGEFI |
0.00
|
-10.17 |
-2.13 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q07955 |
CRIYV |
12.46
|
-6.75 |
1.29 |
|
VVSGL |
12.67
|
-3.44 |
4.60 |
|
NRVVV |
14.40
|
-3.85 |
4.19 |
| Q9P209 |
HGSSV |
4.09
|
-7.20 |
0.84 |
|
EASRA |
9.14
|
-2.39 |
5.65 |
|
GPLPA |
9.67
|
-2.94 |
5.10 |
| Q13155 |
GGAPL |
6.28
|
-6.05 |
1.99 |
| Q5M7Z8 |
NMSEV |
12.51
|
-6.04 |
2.00 |
| Q9BQD3 |
PGSPA |
6.71
|
-3.83 |
4.21 |
|
TTTTI |
9.59
|
-4.78 |
3.26 |
|
DLSHV |
10.26
|
-6.13 |
1.91 |
| Q96CG3 |
GTYSL |
12.73
|
-3.00 |
5.04 |
| P22234 |
TAYPV |
6.80
|
-7.15 |
0.89 |
|
LPSGL |
8.39
|
-3.87 |
4.17 |
|
GCSTV |
9.45
|
-5.25 |
2.79 |
| Q13137 |
SPLSI |
5.82
|
-8.24 |
-0.20 |
|
LPYQV |
6.95
|
-7.01 |
1.03 |
|
SPSPL |
8.07
|
-6.08 |
1.96 |
| Q8IWR9 |
QGSDV |
2.71
|
-8.53 |
-0.49 |
|
QGTGI |
2.74
|
-7.87 |
0.17 |
|
PRSHL |
14.66
|
-1.89 |
6.15 |
| Q8N5Z5 |
QGLGV |
3.82
|
-7.16 |
0.88 |
|
DPANL |
8.67
|
-6.44 |
1.60 |
|
PPLPA |
9.56
|
-4.45 |
3.59 |
| P49247 |
PGSHV |
3.09
|
-7.92 |
0.12 |
|
NSWDL |
10.40
|
-5.71 |
2.33 |
|
VLAPL |
13.65
|
-3.64 |
4.40 |
| Q8TC92 |
PGLGL |
4.96
|
-5.25 |
2.79 |
|
DSICV |
8.45
|
-5.42 |
2.62 |
|
VPVGL |
8.83
|
-4.66 |
3.38 |
| P19012 |
GGMRV |
3.29
|
-9.82 |
-1.78 |
|
GGSLL |
4.39
|
-8.18 |
-0.14 |
|
SASSA |
9.79
|
-1.95 |
6.09 |
| Q9UG07 |
WASLV |
5.18
|
-7.41 |
0.63 |
|
TSSSI |
8.41
|
-4.29 |
3.75 |
|
SLSTI |
10.13
|
-6.38 |
1.66 |
| Q15834 |
GGSGA |
7.23
|
-2.46 |
5.58 |
|
GPSGA |
10.35
|
-1.73 |
6.31 |
|
PELAL |
10.90
|
-3.80 |
4.24 |
| Q96M61 |
QNLPA |
15.00
|
-0.63 |
7.41 |
|
AIAPV |
15.28
|
-4.70 |
3.34 |
| P12931 |
GAFPA |
9.76
|
-3.16 |
4.88 |
|
GPSAA |
10.14
|
-1.40 |
6.64 |
|
KPASA |
11.61
|
-2.06 |
5.98 |
| Q9BVA2 |
GPYCV |
7.18
|
-7.69 |
0.35 |
|
GCSQA |
12.30
|
-0.62 |
7.42 |
|
SRSFV |
12.42
|
-5.40 |
2.64 |
| Q7Z6G3 |
SPTPA |
9.62
|
-3.55 |
4.49 |
|
PAAPA |
10.74
|
-2.28 |
5.76 |
|
TPASA |
11.59
|
-2.32 |
5.72 |
| Q9UQL5 |
FGAQA |
7.85
|
-3.26 |
4.78 |
|
SAFGA |
10.21
|
-2.37 |
5.67 |
|
TTSSA |
14.25
|
1.22 |
9.26 |
| Q9H2P2 |
GQVHV |
12.18
|
-6.36 |
1.68 |
| Q9UJ70 |
GGVVL |
5.27
|
-6.10 |
1.94 |
|
GVVLI |
9.78
|
-8.44 |
-0.40 |
|
