ADAN database
  HOME  
  SEARCH  
 View ADAN database  
  BROWSE  
 HELP 
 Contact us 
 Links 
 Database development 
 
 Search 
 Search 
 Search 
  Advanced search  
  Advanced search  
  Advanced search  
  by Sequence  
  by Sequence  
  by Sequence  
  by PDBsum code  
  by PDBsum code  
  by PDBsum code  
  by Swiss-Prot NAME  
  by Swiss-Prot NAME  
  by Swiss-Prot NAME  
  by Swiss-Prot AC  
  by Swiss-Prot AC  
  by Swiss-Prot AC  
  by Domain or Family  
  by Domain or Family  
  by Domain or Family  
  by Keyword  
  by Keyword  
  by Keyword  
 
 Browse by 
 Browse by 
 Browse by 
 Biochemical Affinity Data 
 Biochemical Affinity Data 
 Biochemical Affinity Data 
 search biochemical affinity data 
 search biochemical affinity data 
 search biochemical affinity data 
 
  Links  
  Links  
  Links  
 PREDIADAN 
 PREDIADAN 
 PREDIADAN 
 Mirrors 
 Mirrors 
 Mirrors 
 What's new 
 What's new 
 What's new 
 Acknowledgement 
 Acknowledgement 
 Acknowledgement 
 Links 
 Links 
 Links 
 Members 
 Members 
 Members 
 References 
 References 
 References 
 Disclaimer 
 Disclaimer 
 Disclaimer 
 Known Problems 
 Known Problems 
 Known Problems 
 Map site 
 Map site 
 Map site 
 
  Database development  
  Database development  
  Database development  
 New ADAN record 
 New ADAN record 
 New ADAN record 
 New AFFINITY data 
 New AFFINITY data 
 New AFFINITY data 
 

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 2R4H2.PDB
Scoring matrix: 2R4H2_mat
Uniprot code: Q96QZ7
Genome source: Homo sapiens
Wild-type ligand: GETSV
Foldx wt ligand score: 3.56
Foldx random average score for Homo sapiens: 10.394

Available information for Q96QZ7 in MINT (Nov 2008):
Nº of interacting proteins: 16
 Proteins belonging to other specie: 10
Nº of interactions described: 16
 Interactions with other species: 10

Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 7744
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 40317
 Total fragments: 18411103
Proteins after random average filtering: 40312
 Total fragments: 9751781
Proteins after disorder filtering: 31666
 Total fragments: 1077561
Proteins after pattern filtering: 24446
 Total fragments: 125926
Proteins after MINT filtering: 3
 Total fragments: 42


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

GETSV

3.56

-8.25

0.00

Best peptides

FMDYM

0.00

-8.38

-0.13

         
Interactors      
Q13625

PAAAV

5.68

-6.45

1.80

GSASV

5.94

-6.83

1.42

GQVSL

5.96

-5.75

2.50

Q14118

PPTEV

4.30

-9.85

-1.60

TETMA

4.41

-6.33

1.92

PPFTV

4.73

-8.98

-0.73

P20936

VETGV

3.62

-9.89

-1.64

GDYSL

3.86

-7.96

0.29

GGAAL

6.12

-4.71

3.54

 


    Comments or questions on the site? Send a mail to adandatabase@umh.es                                                     
DISCLAIMER