ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 2PZD2.PDB
Scoring matrix: 2PZD2_mat
Uniprot code: O43464
Genome source: Homo sapiens
Wild-type ligand: GWTMFWV
Foldx wt ligand score: 1.88
Foldx random average score for Homo sapiens: 15.856

Available information for O43464 in MINT (Nov 2008):
Nš of interacting proteins: 5
 Proteins belonging to other specie: 0
Nš of interactions described: 7
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 14587
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 33474
 Total fragments: 13969987
Proteins after random average filtering: 33465
 Total fragments: 8838762
Proteins after disorder filtering: 25300
 Total fragments: 762962
Proteins after pattern filtering: 19064
 Total fragments: 93043
Proteins after MINT filtering: 1
 Total fragments: 2


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

GWTMFWV

1.88

-19.84

0.00

Best peptides

WWWMMWI

0.00

-17.28

2.56

         
Interactors      
Q99982

FKKHFPV

12.06

-14.00

5.84

EILPSSL

14.70

-11.98

7.86

 


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