ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 2PKU2.PDB
Scoring matrix: 2PKU2_mat
Uniprot code: Q9EP80
Genome source: Rattus norvegicus
Wild-type ligand: ESVKI
Foldx wt ligand score: 6.64
Foldx random average score for Rattus norvegicus: 7.985

Available information for Q9EP80 in MINT (Nov 2008):
Nš of interacting proteins: 15
 Proteins belonging to other specie: 1
Nš of interactions described: 58
 Interactions with other species: 1

Genome scanning information:
Subcellular location: True
Proteins in genome Rattus norvegicus: 15006
Proteins located in other compartments: 2291
Proteins considered as fragments or having non-standard amino acids: 3052
Total scanned proteins: 9663
 Total fragments: 4598028
Proteins after random average filtering: 9663
 Total fragments: 2453594
Proteins after disorder filtering: 7675
 Total fragments: 231174
Proteins after pattern filtering: 5706
 Total fragments: 24242
Proteins after MINT filtering: 10
 Total fragments: 42


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

ESVKI

6.64

-6.74

0.00

Best peptides

EMWMM

0.00

-7.80

-1.06

         
Interactors      
Q62962

LLTTV

5.91

-5.85

0.89

P31421

GLFPV

5.18

-6.95

-0.21

ASANL

6.12

-6.16

0.58

APTAV

6.44

-3.13

3.61

P31422

ADSIV

4.63

-6.04

0.70

PTADL

7.10

-1.02

5.72

P18088

TSSNA

7.07

-1.12

5.62

SNAGA

7.53

-2.30

4.44

NTTNL

7.72

-2.75

3.99

P19493

DTMKV

3.43

-7.98

-1.24

KGYGV

5.75

-6.25

0.49

NEFGI

7.69

-6.38

0.36

P19492

DTMKV

3.43

-7.98

-1.24

KGYGV

5.75

-6.25

0.49

NEFGI

7.69

-6.38

0.36

P19491

DTMKV

3.43

-7.98

-1.24

KGYGI

7.45

-5.70

1.04

P35400

GLFPV

5.18

-6.95

-0.21

GPSGV

6.13

-4.02

2.72

AGTPV

6.84

-3.60

3.14

P97879

PPAMV

2.50

-8.28

-1.54

YPSTV

5.67

-5.23

1.51

KLSDV

5.78

-5.46

1.28

P05696

HKFKI

5.42

-7.53

-0.79

PYVKL

7.06

-5.74

1.00

 


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