ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 2PDZ2.PDB
Scoring matrix: 2PDZ2_mat
Uniprot code: Q61234
Genome source: Mus musculus
Wild-type ligand: KESLV
Foldx wt ligand score: 4.2
Foldx random average score for Mus musculus: 9.376

Available information for Q61234 in MINT (Nov 2008):
Nš of interacting proteins: 4
 Proteins belonging to other specie: 2
Nš of interactions described: 11
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Mus musculus: 58346
Proteins located in other compartments: 6057
Proteins considered as fragments or having non-standard amino acids: 13900
Total scanned proteins: 38389
 Total fragments: 17621316
Proteins after random average filtering: 38389
 Total fragments: 11957758
Proteins after disorder filtering: 30295
 Total fragments: 1665373
Proteins after pattern filtering: 22843
 Total fragments: 127518
Proteins after MINT filtering: 1
 Total fragments: 4


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

KESLV

4.20

-2.96

0.00

Best peptides

PMGFI

0.00

3.37

6.33

         
Interactors      
P11531

GLSPL

6.49

1.49

4.45

DSAPA

7.07

1.66

4.62

QHLEA

8.00

0.27

3.23

 


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