ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 2P4R2.PDB
Scoring matrix: 2P4R2_mat
Uniprot code: O55043
Genome source: Rattus norvegicus
Wild-type ligand: RPPRPSRPPPPTP
Foldx wt ligand score: 3.54
Foldx random average score for Rattus norvegicus: 13.460

Available information for O55043 in MINT (Nov 2008):
Nš of interacting proteins: 5
 Proteins belonging to other specie: 0
Nš of interactions described: 6
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Rattus norvegicus: 15006
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 3052
Total scanned proteins: 11953
 Total fragments: 5508495
Proteins after random average filtering: 11945
 Total fragments: 2767113
Proteins after disorder filtering: 8456
 Total fragments: 204190
Proteins after pattern filtering: 6082
 Total fragments: 94488
Proteins after MINT filtering: 5
 Total fragments: 648


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

RPPRPSRPPPPTP

3.54

-18.51

0.00

Best peptides

RYKRPRRHPMDIP

0.00

-19.74

-1.23

         
Interactors      
P35465

HGSKPLPPNPEEK

9.02

-11.98

6.53

PPAPPMRNTSTMI

9.23

-13.62

4.89

VQDKPPAPPMRNT

9.46

-12.26

6.25

Q9QX74

GFVIPPPAPPPPP

6.56

-15.44

3.07

VFSLPSQSPAGDL

7.50

-12.06

6.45

IPPPPQSVPPSPP

7.58

-15.89

2.62

Q9Z272

RQPPGPVPVPSLP

11.14

-12.28

6.23

LRQPPGPVPVPSL

11.24

-11.89

6.62

PSLPSERAEHTLM

11.31

-10.62

7.89

Q9JLU4

RPKRRPRPSGPDS

6.21

-12.11

6.40

GPGRRAESPCAPL

7.37

-15.88

2.63

IPPPPQTAPPPPP

7.38

-16.63

1.88

Q9WV48

SYDRPSFLPPGPG

6.51

-14.46

4.05

IPPPPTTSPPEPP

7.33

-15.88

2.63

LPPRPLVHPLTGK

7.79

-14.51

4.00

 


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