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Matrix information:
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ADAN-name: 2OPG2.PDB
Scoring matrix: 2OPG2_mat
Uniprot code: O75970
Genome source: Homo sapiens
Wild-type ligand: YKSTRL
Foldx wt ligand score: 5.71
Foldx random average score for Homo sapiens: 9.202 Available information for O75970 in MINT (Nov 2008):
Nš of interacting proteins: 6
Proteins belonging to other specie: 1
Nš of interactions described: 17
Interactions with other species: 5
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 7744
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 40317
Total fragments: 18370238
Proteins after random average filtering: 40308
Total fragments: 9799480
Proteins after disorder filtering: 31089
Total fragments: 658034
Proteins after pattern filtering: 24785
Total fragments: 134337
Proteins after MINT filtering: 1
Total fragments: 4
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
YKSTRL |
5.71
|
-10.63 |
0.00 |
| Best peptides |
WWLMFF |
0.00
|
-9.95 |
0.68 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q9HB19 |
LPSSRI |
6.59
|
-8.07 |
2.56 |
|
QPWTPV |
6.64
|
-9.32 |
1.31 |
|
GPNSIL |
7.02
|
-8.40 |
2.23 |
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