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Matrix information:
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ADAN-name: 2OJ22.PDB
Scoring matrix: 2OJ22_mat
Uniprot code: P08631
Genome source: Homo sapiens
Wild-type ligand: HSKYPLPPLPSL
Foldx wt ligand score: 8.95
Foldx random average score for Homo sapiens: 11.544 Available information for P08631 in MINT (Nov 2008):
Nš of interacting proteins: 16
Proteins belonging to other specie: 7
Nš of interactions described: 37
Interactions with other species: 17
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 7698
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 40363
Total fragments: 18147411
Proteins after random average filtering: 40336
Total fragments: 11159972
Proteins after disorder filtering: 29512
Total fragments: 1017156
Proteins after pattern filtering: 21449
Total fragments: 370608
Proteins after MINT filtering: 6
Total fragments: 355
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
HSKYPLPPLPSL |
8.95
|
-3.50 |
0.00 |
| Best peptides |
NMRMHKPPLRFG |
0.00
|
1.02 |
4.52 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q92556 |
IPDAPPPIPKEP |
7.26
|
-4.52 |
-1.02 |
|
QIPDAPPPIPKE |
11.52
|
-0.61 |
2.89 |
| O43516 |
GPRPPLPPDRPS |
3.75
|
-8.53 |
-5.03 |
|
GSRPPLLPPGGR |
5.93
|
-4.50 |
-1.00 |
|
RNRMPPPRPDVG |
6.01
|
-4.34 |
-0.84 |
| Q13177 |
EDKPPAPPVRMS |
5.25
|
-6.50 |
-3.00 |
|
DKPPAPPVRMSS |
7.59
|
-4.02 |
-0.52 |
|
ANHSLKPLPSVP |
8.97
|
-4.72 |
-1.22 |
| P42768 |
TPRGPPPPGRGG |
4.76
|
-4.35 |
-0.85 |
|
GIAPPPPTPRGP |
5.67
|
-5.22 |
-1.72 |
|
GPLPPPPPGAGG |
6.05
|
-3.67 |
-0.17 |
| Q13444 |
GPAKPPPPRKPL |
5.71
|
-4.43 |
-0.93 |
|
SERPGPPQRALL |
6.69
|
-4.02 |
-0.52 |
|
PSERPGPPQRAL |
6.85
|
-5.99 |
-2.49 |
| P21860 |
HPVPIMPTAGTT |
7.13
|
-2.15 |
1.35 |
|
PGIAPGPEPHGL |
8.20
|
-3.80 |
-0.30 |
|
PVTPLSPPGLEE |
8.38
|
-4.26 |
-0.76 |
|
