ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 2JIL2.PDB
Scoring matrix: 2JIL2_mat
Uniprot code: Q9Y3R0
Genome source: Homo sapiens
Wild-type ligand: VSETAV
Foldx wt ligand score: 5.36
Foldx random average score for Homo sapiens: 10.083

Available information for Q9Y3R0 in MINT (Nov 2008):
Nš of interacting proteins: 9
 Proteins belonging to other specie: 0
Nš of interactions described: 16
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 7284
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 40777
 Total fragments: 18602106
Proteins after random average filtering: 40771
 Total fragments: 10908684
Proteins after disorder filtering: 31804
 Total fragments: 871248
Proteins after pattern filtering: 24745
 Total fragments: 128338
Proteins after MINT filtering: 6
 Total fragments: 81


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

VSETAV

5.36

-10.80

0.00

Best peptides

EMMDML

0.00

-14.18

-3.38

         
Interactors      
P04150

PPKLCL

4.06

-8.56

2.24

DDSFLL

4.82

-9.83

0.97

DNLTSL

5.40

-9.72

1.08

Q9BZL6

PGGLEL

5.71

-6.55

4.25

LPGSGL

6.81

-7.89

2.91

LPQIPA

7.53

-9.78

1.02

Q14653

DPGMSL

4.87

-7.21

3.59

LPGWPV

5.42

-9.34

1.46

PPSLAV

6.26

-9.06

1.74

Q63ZY3

ELCLDL

3.67

-9.20

1.60

RSELCL

4.97

-7.43

3.37

SEVASL

6.08

-9.27

1.53

Q9Y6Q9

IPTLPL

4.29

-9.36

1.44

DYNTSL

5.45

-10.16

0.64

DSKSPL

5.88

-12.64

-1.84

P49683

PRVSDL

6.63

-11.75

-0.95

DLFSGL

7.19

-8.43

2.37

AVTTPA

8.22

-8.91

1.89

 


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