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Matrix information:
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ADAN-name: 2IWP2.PDB
Scoring matrix: 2IWP2_mat
Uniprot code: O75970
Genome source: Homo sapiens
Wild-type ligand: VSETSV
Foldx wt ligand score: 4.17
Foldx random average score for Homo sapiens: 11.268 Available information for O75970 in MINT (Nov 2008):
Nš of interacting proteins: 6
Proteins belonging to other specie: 1
Nš of interactions described: 17
Interactions with other species: 5
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 7744
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 40317
Total fragments: 18370238
Proteins after random average filtering: 40314
Total fragments: 13536575
Proteins after disorder filtering: 32316
Total fragments: 1801328
Proteins after pattern filtering: 25140
Total fragments: 145056
Proteins after MINT filtering: 1
Total fragments: 4
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
VSETSV |
4.17
|
-9.58 |
0.00 |
| Best peptides |
LEIIDV |
0.00
|
-10.54 |
-0.96 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q9HB19 |
QPWTPV |
3.03
|
-11.94 |
-2.36 |
|
LPSSRI |
6.95
|
-7.08 |
2.50 |
|
PGSSSL |
7.36
|
-7.99 |
1.59 |
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